Effect of Kinetic Chain Exercises on Muscle Strength, Joint Position Sense and Quality of Life in Children with Haemophilia.

NCT ID: NCT06649175

Last Updated: 2024-10-21

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-11-01
• Study Completion Date: 2025-03-01

Brief Summary

The goal of this clinical trial is to learn if there are effect of close kinetic chain exercises on muscle strength, joint position sense and Quality of life in children with haemophilia? Null hypothesis

It will be hypothesized that:

There is no effect of close kinetic chain exercises on muscle strength, joint position sense and Quality of life in children with haemophilia.

Detailed Description

Sample size estimation will be carried out to determine the recruited number of children selected randomly from Out Patient clinic of Atfal Misr hospital, Cairo governorate to participate in this study. The study targets male children with hemophilia A.

They will be selected based on the following:

Inclusion criteria:

1. Their chronological age will be 5-7yeasr.

2. All children will receive prophylaxis therapy.

3. They will able to stand and walk independently.

4. They will be able to follow instructions during evaluation and treatment.

Exclusive criteria:

The children will be excluded if they have one of the following:

1. Visual or auditory problem.

2. Radiographic changes as bone erosions, destruction, or joint subluxation, or congenital or acquired skeletal deformities in both lower limbs.

3. Surgical procedures performed six weeks prior to or during study.

4. Bleeding in joint 2 week prior to assessment.

Conditions

Hemophilia a; Muscle Strength; Joint Position Sense; Quality of Life (QOL)

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

group(A):exercise group.

Control Group (A): will receive the traditional physical therapy (PT) program for one hour two times weekly for six successive weeks.

Intervention: traditional physical therapy program.

Group Type: ACTIVE_COMPARATOR

Exercise

Intervention Type: OTHER

Control Group (A): will receive the traditional physical therapy (PT) , the traditional physical therapy program will include the following:

• Stretching exercise for shortening muscle of lower limbs (LL) mainly (hip flexors, adductors, knee flexors and ankle planter flexors).
• Balance training from standing while giving perturbations.
• Balance board training.
• Step ups: repeated stepping anteriorly and laterally onto a step with both legs alternatively, progressing to higher step and decreasing upper extremity support.
• Forward and backward walking (with or without handheld mobility devices).
• Side walking (with or without handheld mobility devices).
• Walking in astride line (with or without handheld mobility devices).

Group(B): modified exercise group.

Group (B): will receive a program of close kinetic chain exercises for 30 min.

Group Type: ACTIVE_COMPARATOR

Exercise

Intervention Type: OTHER

Close kinetic chain (CKC) exercises :

1. Supine wall push exercise: Start position: supine with the both leg against wall, other limb straight. Exercise action: push against wall for thirty seconds.

2. Wall push against Swiss ball exercise: Start position: Supine with a Swiss ball between patient's legs and the wall. Exercise action: push against the wall for thirty seconds.

3. Supine half bridging exercise: Start position: Lying on back, knees bent Exercise action: keeping spine neutral and hinging up from the hips, move into a bridge.

Interventions

Exercise

Close kinetic chain (CKC) exercises :

1. Supine wall push exercise: Start position: supine with the both leg against wall, other limb straight. Exercise action: push against wall for thirty seconds.

2. Wall push against Swiss ball exercise: Start position: Supine with a Swiss ball between patient's legs and the wall. Exercise action: push against the wall for thirty seconds.

3. Supine half bridging exercise: Start position: Lying on back, knees bent Exercise action: keeping spine neutral and hinging up from the hips, move into a bridge.

Intervention Type: OTHER

Exercise

Control Group (A): will receive the traditional physical therapy (PT) , the traditional physical therapy program will include the following:

• Stretching exercise for shortening muscle of lower limbs (LL) mainly (hip flexors, adductors, knee flexors and ankle planter flexors).
• Balance training from standing while giving perturbations.
• Balance board training.
• Step ups: repeated stepping anteriorly and laterally onto a step with both legs alternatively, progressing to higher step and decreasing upper extremity support.
• Forward and backward walking (with or without handheld mobility devices).
• Side walking (with or without handheld mobility devices).
• Walking in astride line (with or without handheld mobility devices).

Intervention Type: OTHER

Other Intervention Names

Close Kinetic Chain Exercise (CKC); Traditional physical therapy program

Eligibility Criteria

Inclusion Criteria

• 1. Their chronological age will be 5-7yeasr. 2. All children will receive prophylaxis therapy. 3. They will able to stand and walk independently. 4. They will be able to follow instructions during evaluation and treatment.

Exclusion Criteria

• The children will be excluded if they have one of the following:

1. Visual or auditory problem.

2. Radiographic changes as bone erosions, destruction, or joint subluxation, or congenital or acquired skeletal deformities in both lower limbs.

3. Surgical procedures performed six weeks prior to or during study.

4. Bleeding in joint 2 week prior to assessment.

• Minimum Eligible Age: 5 Years
• Maximum Eligible Age: 7 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: No

Sponsors

Cairo University

OTHER

Sponsor Role: lead

Responsible Party

Yasmein Nabil Mohamed El Tanany

Physiotherapist

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Out Patient clinic of Atfal Misr hospital

Cairo, , Egypt

Countries

Egypt

Central Contacts

YASMEIN EL-TANANY, M.Sc. in Physical Therapy

Role: CONTACT

10722018587060@pg.cu.edu.eg

00201065080993

Facility Contacts

NAGLAA SHAHEN

Role: primary

m.refat2006@yahoo.com

00201005183031 ext. PRO.DR

Other Identifiers

P.T.REC/012/005128

Identifier Type: -

Identifier Source: org_study_id