Radiological and Clinical Measures as Predictors of Dynamic Postural Control Deficits in Chronic Ankle Instability

NCT ID: NCT07051018

Last Updated: 2025-07-03

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 50 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-07-15
• Study Completion Date: 2025-09-20

Brief Summary

The purpose of this study is to investigate the association between dynamic postural control and clinical measures of (ankle and hip strength, ankle DFROM and position sense) and radiological measures in patients with unilateral CAI.

Detailed Description

Ankle sprains are among the most frequent injuries seen in emergency departments and in sports injury clinics. Among all ankle injuries, ankle sprains are the most common and account for approximately 80% of which 77% are lateral sprains. Ankle sprain incidence ranges from 5.3- 7.0 sprained ankles per one thousand persons per year in Europe and is estimated to be 23,000 ankle sprains occur per day in the United States. Up to 74% of individuals who sprained their ankle experience ongoing problems that prevent them from participating in sports and other physical activities. Lateral ankle sprain (LAS) typically occurs when the rear foot is supinated, and the leg is externally rotated. Inversion injuries affect the lateral ankle ligaments and subtalar ligaments concomitantly; around 73% of lateral ankle sprains are due to rupture or tear of the Anterior Talo-Fibular Ligament (ATFL), followed by Calcaneo Fibular Ligament (CFL) and cervical ligament of the subtalar joint with the interosseous talocalcaneal ligament respectively.

HYPOTHESES:

It will be hypothesized that:

1. There will be no relation between the radiological measures of the ankle joint and dynamic postural control in patients with unilateral CAI.

2. There will be no relation between hip muscles strength and dynamic postural control in patients with unilateral CAI.

3. There will be no relation between ankle performance (muscle strength, DFROM and position sense) and dynamic postural control in patients with unilateral CAI.

4. There will be a non-significant difference in the dynamic postural control between affected and normal lower limb.

5. There will be a non-significant difference in the radiological measures between affected and normal lower limb.

6. There will be a non-significant difference in the ankle performance between affected and normal lower limb.

7. There will be a non-significant difference in the muscle strength around the hip joint between the affected and normal lower limb.

Conditions

Chronic Ankle Instability, CAI

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

1. At least one significant unilateral lateral ankle sprain in which the subject was unable to walk independently without the aid of crutches (the first sprain occurred more than 12 months ago).

2. Repeated bouts of lateral ankle injury (last injury had to be more than three months prior to inclusion in the study).

3. Feeling of ankle instability "giving way", at least 2 episodes in the last 6 months (Terada et al., 2014).

4. Pain during intense loading.

5. The Cumberland Ankle Instability Tool (CAIT) ≤ 24.

6. Age range of 18-30 years (Delahunt et al., 2010).

1. A previous trauma or surgery to the trunk or lower extremities other than an ankle sprain.

2. Neurological or vestibular impairments with remaining deficits.

3. No participant with CAI had acutely sprained his or her ankle in the 3 months prior to the testing.

4. Participants will be excluded if they have participated in any rehabilitation in the past 6 months.

5. Concussion or head injury or lower back pain in the past 6 months.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 30 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Cairo University

OTHER

Sponsor Role: lead

Responsible Party

Rana Seif El-Eslam Youssif El-Said

Lecturer Assistant at faculty of physical therapy- University of Hertfordshire

Responsibility Role: PRINCIPAL_INVESTIGATOR

Central Contacts

Rana Seif Youssif, Lecturer Assistant

Role: CONTACT

rana_seif_pt@hotmail.com

002 01014596607

Other Identifiers

P.T.REC/012/005628

Identifier Type: -

Identifier Source: org_study_id