Visuo-Tactile Integration and Body Ownership in the Human Brain

NCT ID: NCT05164991

Last Updated: 2023-09-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-10

Study Completion Date

2023-09-12

Brief Summary

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The present project exploits brain imaging and neuroscience robotics to investigate the role of quantifiable visual input on the relationship between visuo-tactile integration and body ownership (the feeling that "this" body belongs to "me").

Detailed Description

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Observational study, fundamental research, multicentric, national. The analysis of questionnaires, self-reports, and brain imaging associated with the RHI is used to understand the influence of visual input on body ownership. To this aim, participants lay down in the magnetic resonance (MR) scanner (Figure 1B), are presented with visual stimuli (videos of the virtual rubber hand - visual stroking) simultaneously in real time with tactile stimuli (robotic stroking of the participant's hand - tactile stroking), and in combination or not with the measurement of autonomic arousal (GSR) associated with the observation of a video showing the virtual rubber hand in a threatening situation (e.g. a knife approaching the virtual hand - unconscious RHI effects). By means of structured questionnaires and semi-structured self-reports, participants (i) evaluate eventual sensations felt during the visuo-tactile stimulation and (ii) report the personal feelings and impressions about body ownership for the virtual rubber hand (conscious RHI effects).

Conditions

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Behavior and Behavior Mechanisms Body Representation

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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MR imaging

The experiment is aimed to induce a virtual rubber hand illusion, in which the individuals can potentially experience an embodiment illusion

Group Type EXPERIMENTAL

Visuo-tactile stimulations of the right hand

Intervention Type BEHAVIORAL

Participants lay down in the magnetic resonance (MR) scanner are presented with visual stimuli (videos of the virtual rubber hand - visual stroking) simultaneously in real time with tactile stimuli (robotic stroking of the participant's hand - tactile stroking). An MR-compatible robot systematically provides the tactile stroking on the participant's hand. MR-compatible goggles show the visual stroking. Patterns of long and short robotic movements will be provided.

Interventions

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Visuo-tactile stimulations of the right hand

Participants lay down in the magnetic resonance (MR) scanner are presented with visual stimuli (videos of the virtual rubber hand - visual stroking) simultaneously in real time with tactile stimuli (robotic stroking of the participant's hand - tactile stroking). An MR-compatible robot systematically provides the tactile stroking on the participant's hand. MR-compatible goggles show the visual stroking. Patterns of long and short robotic movements will be provided.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* general health
* personal interest
* age between 18 and 55 years old
* fulfil standard guidelines for fMRI studies

Exclusion Criteria

* history of seizures, epilepsy
* specific medications or treatment
* concomitant diseases (e.g. cardiopathy)
* pregnancy
* unexplained loss of consciousness
* chronic headaches
* neurological illnesses
* head concussion,
* presence of metal in the neck or head
* implanted medical devices
* drug abuse
* inability to give consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Psychiatric University Hospital, Zurich

OTHER

Sponsor Role collaborator

Eye Hospital Jules Gonin

OTHER

Sponsor Role collaborator

Swiss Federal Institute of Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Silvio Ionta, Professor

Role: PRINCIPAL_INVESTIGATOR

Fondation Asile des Aveugles, 1002, Lausanne

Locations

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ETH Zurich, Rehabilitation Engeineering Laboratory

Zurich, , Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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2021-0111

Identifier Type: -

Identifier Source: org_study_id

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