Probing Neural Circuitry for the Control of Movement

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-05-31

Study Completion Date

2020-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The investigators are interested in examining 1) the basic organization of spinal and cortical circuitry for the control of movement and 2) the influence of injury of these circuits. To investigate the neuronal circuitry, the investigators use various types of mechanical or electrical stimulation of the limbs, transcranial magnetic stimulation of the cortex and galvanic vestibular stimulation in both uninjured human subjects and subjects with a neurological injury (such as spinal cord injury, or Parkinsons's disease).

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Movement-Related Brain Networks Involved in Hand Dystonia

NCT00137384

Movement Disorder Focal Dystonia

COMPLETED

Transcranial Magnetic Stimulation and Electrical Stimulation of Nerves to Study Focal Dystonia

NCT00050024

Dystonic Disorders

COMPLETED

Transcranial Magnetic Stimulation to Study Imagination of Movement

NCT00046215

Healthy

COMPLETED

Neurophysiology of Surround Inhibition in the Human Motor Cortex

NCT03018262

Normal Physiology

COMPLETED

Surround Inhibition in Patients With Dystonia

NCT00029601

Dystonic Disorders Healthy

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Neurological Movement Disorders

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Neurological Injury

No interventions assigned to this group

No Neurological Injury

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* control subjects: no neurological movement disorder
* patients: neurological movement disorder

Exclusion Criteria

patients and control subjects:

* presence of any central psychiatric disorder that precludes subject from giving informed and voluntary consent
* presence of any cardiovascular conditions or limitations that restrict the ability to walk on a treadmill continuously for more than 20 minutes
* for the electrical stimulation examination, subjects with metal implants are also excluded
* for the TMS and GVS examination, subjects with the following conditions are excluded: metal implants in the head, cardiac pacemakers, history of migraine headaches, history of major head injury, history of stroke, history of seizures, previous brain neurosurgery, unstable medical conditions, major psychiatric disorders, pregnancy -

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes