Evaluation of Peroral Endoscopic Myotomy to Treat Zenker's Diverticulum

NCT ID: NCT05157984

Last Updated: 2024-03-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

38 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-25

Study Completion Date

2024-06-28

Brief Summary

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This is a multicenter investigator-initiated trial between Baylor-Scotts \& White (BSW) and Methodist Health System (MHS). This study will be conducted via a retrospective review and a prospective patient registry. Patients who have undergone the ZPOEM procedure performed by the physicians listed in this protocol will be included, as well as patients who will have this procedure in the future. Data that will be collected at MHS will be entered into an Excel spreadsheet. Patient demographic information will be collected via a review of subjects' electronic medical records. Available patient outcomes will be collected via a review of electronic medical records. This review will be conducted from 1/1/2017 through 12/31/2025.

Detailed Description

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This is a multicenter investigator-initiated trial between Baylor-Scotts \& White (BSW) and Methodist Health System (MHS). This study will be conducted via a retrospective review and a prospective patient registry. Patients who have undergone the ZPOEM procedure performed by the physicians listed in this protocol will be included, as well as patients who will have this procedure in the future. Data that will be collected at MHS will be entered into an Excel spreadsheet. Patient demographic information will be collected via a review of subjects' electronic medical records. Available patient outcomes will be collected via a review of electronic medical records. This review will be conducted from 1/1/2017 through 12/31/2025.

To obtain the follow-up information, potential subjects will be identified using the same process described in the previous paragraph and will be contacted by a member of the institution's research team to answer questions about their symptoms post-surgery. These are listed in the ZPOEM Data Collection Sheet. These questions may be administered over the phone, via email, or by mail. Subjects enrolled in the patient registry will have follow-up data collected at 2-time points: 2 weeks post-op and 3 months post-op.

Primary endpoints and other variables to be collected are those listed on the ZPOEM Data Collection Sheet. Primary subject endpoints include, but are not limited to:

* Dysphagia score(s) - depending on what is available in EMR
* Weight gain following surgery

Conditions

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Zenker Diverticulum

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Study Groups

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Retrospective cohort

Any patient of the physicians listed in this study who has undergone the ZPOEM procedure to treat ZD at Methodist Health System

ZPOEM

Intervention Type PROCEDURE

Zenker's diverticulum management by Per oral endoscopic myotomy (POEM)

Prospective cohort

Any patient of the physicians listed in this study who has undergone the ZPOEM procedure to treat ZD at Methodist Health System and has agreed to be follow-up post-procedure.

ZPOEM

Intervention Type PROCEDURE

Zenker's diverticulum management by Per oral endoscopic myotomy (POEM)

Interventions

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ZPOEM

Zenker's diverticulum management by Per oral endoscopic myotomy (POEM)

Intervention Type PROCEDURE

Other Intervention Names

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peroral endoscopic myotomy (POEM)

Eligibility Criteria

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Inclusion Criteria

* Patients 18 years of age or older
* Any patient of the physicians listed in this study who has undergone the ZPOEM procedure to treat ZD at MHS
* For prospective registry: Ability to give informed consent

Exclusion Criteria

* For prospective registry: Unable or not willing to provide informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Baylor Scott and White Health

OTHER

Sponsor Role collaborator

Methodist Health System

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Prashant Kedia, MD

Role: PRINCIPAL_INVESTIGATOR

Methodist Health System

Locations

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Methodist Dallas Medical Center

Dallas, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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2020.11.16

Identifier Type: OTHER

Identifier Source: secondary_id

031.GID.2021.D

Identifier Type: -

Identifier Source: org_study_id

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