Effects of Dexamethasone on Common Bile Duct Cannulation Time
NCT ID: NCT05945797
Last Updated: 2025-03-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
80 participants
INTERVENTIONAL
2023-08-01
2024-05-16
Brief Summary
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Participants will be divided into two groups, treatment group and placebo group. Patients in treatment group will receive dexamethasone and those in placebo group will be given normal saline before undergoing ERCP. The results in both groups will be compared to determine the effects of dexamethasone.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Dexa Arm
Experimental arm patients will be receiving 2 ml (4mg) of dexamenthasone prior to undergoing ERCP.
Dexamethasone 4mg
An injection of 4mg of dexamethasone will be given to patients approximately 2 to 4 hours prior to the procedure of ERCP.
NS Arm
Placebo arm patients will be receiving 2 ml of normal saline prior to undergoing ERCP.
Dexamethasone 4mg
An injection of 4mg of dexamethasone will be given to patients approximately 2 to 4 hours prior to the procedure of ERCP.
Interventions
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Dexamethasone 4mg
An injection of 4mg of dexamethasone will be given to patients approximately 2 to 4 hours prior to the procedure of ERCP.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Both genders, male and female patients
Exclusion Criteria
* Pregnant females
* Pre existing stent in CBD or pancreatic duct
* Previous history of ERCP
* Patients with billroth II surgery
* Anatomical abnormalities
* Lack of competence in patients
* Roux en Y gastric bypass
* Patients with contra indications for steroids like DM
18 Years
ALL
No
Sponsors
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Gujranwala medical college District Headquarters Hospital, Gujranwala
OTHER
Responsible Party
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Principal Investigators
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Najam us Sehar Saeed, FCPS-Gastro
Role: STUDY_CHAIR
GMC-DHQ Hospital, Gujwanala, Pakistan
Locations
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Gujranwala Medical College Hospital
Gujranwala, Punjab Province, Pakistan
Countries
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References
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Sherman S, Lehman GA. Endoscopic retrograde cholangiopancreatography, endoscopic sphincterotomy and stone removal, and endoscopic biliary and pancreatic drainage. In: Yamada T, et al. (eds.) Text book of gastroenterology. 3rd edn. Philadelphia: Lippincott, Williams & Wilkins ; 1999: 2718 - 2746
Wehrmann T, Schmitt T, Stergiou N, Caspary WF, Seifert H. Topical application of nitrates onto the papilla of Vater: manometric and clinical results. Endoscopy. 2001 Apr;33(4):323-8. doi: 10.1055/s-2001-13687.
Allescher HD, Neuhaus H, Hagenmuller F, Classen M. Effect of N-butylscopolamine on sphincter of Oddi motility in patients during routine ERCP--a manometric study. Endoscopy. 1990 Jul;22(4):160-3. doi: 10.1055/s-2007-1012829.
Sola-Bonada N, de Andres-Lazaro AM, Roca-Massa M, Bordas-Alsina JM, Codina-Jane C, Ribas-Sala J. [1.6% peppermint oil solution as intestinal spasmolytic in retrograde endoscopic cholangiopancreatography]. Farm Hosp. 2012 Jul-Aug;36(4):256-60. doi: 10.1016/j.farma.2011.08.003. Epub 2011 Dec 1. Spanish.
Devereaux BM, Lehman GA, Fein S, Phillips S, Fogel EL, Sherman S. Facilitation of pancreatic duct cannulation using a new synthetic porcine secretin. Am J Gastroenterol. 2002 Sep;97(9):2279-81. doi: 10.1111/j.1572-0241.2002.05982.x.
Other Identifiers
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001
Identifier Type: -
Identifier Source: org_study_id
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