Comparative Analysis of Serum Lipid Profiles in Patients With and Without Gallstones

NCT ID: NCT03804775

Last Updated: 2019-01-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-08-01

Study Completion Date

2018-08-30

Brief Summary

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Gallbladder disease is one of the most common diseases of the gastrointestinal tract. Various studies have shown an association between gallstones and an alteration in the serum lipids. The objective of this study will be to compare serum lipid profile of gallstone patients with the controls.

Detailed Description

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This prospective cross-sectional study will be conducted in the Surgical Department of the Services Institute of Medical Sciences. A total of 50 patients will beincluded in the study after screening through the inclusion criteria. A control group of 50 inpatients with no personal or family history of gallstones will be also recruited for comparison. Results will be expressed as mean with standard deviation. Students t- test will be used to compare the data between the patients and the control groups (p\<0.05 will be considered statistically significant). SPSS software, version 20 will be used for statistical analysis.

Conditions

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Gallstone Dyslipidemias

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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case group

patients presenting with gallstone disease

Serum lipid profile

Intervention Type DIAGNOSTIC_TEST

Blood samples drawn from the patients and controls will be analyzed for serum cholesterol, serum triglycerides, serum LDLs and serum HDL levels. All the results will be recorded on a performa

control group

inpatients with no history of gallstones

Serum lipid profile

Intervention Type DIAGNOSTIC_TEST

Blood samples drawn from the patients and controls will be analyzed for serum cholesterol, serum triglycerides, serum LDLs and serum HDL levels. All the results will be recorded on a performa

Interventions

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Serum lipid profile

Blood samples drawn from the patients and controls will be analyzed for serum cholesterol, serum triglycerides, serum LDLs and serum HDL levels. All the results will be recorded on a performa

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Male or female patients with the gall stone disease
* Age from 20 to 70 years
* Gallstones were diagnosed through the ultrasound

Exclusion Criteria

* Patients with acalculous gallbladder disease on ultrasound,
* Patients with terminal ileal resection,
* Patients with hemolytic diseases (hereditary spherocytosis, sickle cell anemia on history and CBC film),
* Patients with liver cirrhosis (on abdominal ultrasound) and
* Patients on antihyperlipidemic drugs
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Services Hospital, Lahore

OTHER_GOV

Sponsor Role lead

Responsible Party

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Dr. SamiUllah

Principle investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mahmmood Ayyaz, mbbs, fcps

Role: STUDY_DIRECTOR

Services Hospital, Lahore

Locations

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Services hospital

Lahore, Punjab Province, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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s10

Identifier Type: -

Identifier Source: org_study_id

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