SpyGlass AMEA Registry

NCT ID: NCT02281019

Last Updated: 2019-07-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

526 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-11-15

Study Completion Date

2016-10-18

Brief Summary

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The purpose of this study is to document indications for cholangioscopy and clinical utility of the SpyGlass Direct Visualization System (DVS) throughout the AMEA (Asia, Middle-East, Africa) region when used per standard of practice.

Detailed Description

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Conditions

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Biliary Stricture Biliary Obstruction Due to Common Bile Duct Stone Periampullary Tumor Hemobilia

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Indeterminate strictures or undefined filling defects

ERCP (Endoscopic Retrograde Cholangiopancreatography)

Intervention Type PROCEDURE

ERCP procedure will be performed to visualize bile ducts.

SpyGlass DVS and SpyGlass Digital Simple (DS)

Intervention Type DEVICE

Cholangioscopy using SpyGlass™ DVS or SpyGlass DS will be performed post ERCP for direct viewing of the bile ducts. What is seen during the procedure will determine a course of treatment. Among the options are biopsies taken, stones treated/removed, or a stent placed

Biliary stone cases

ERCP (Endoscopic Retrograde Cholangiopancreatography)

Intervention Type PROCEDURE

ERCP procedure will be performed to visualize bile ducts.

SpyGlass DVS and SpyGlass Digital Simple (DS)

Intervention Type DEVICE

Cholangioscopy using SpyGlass™ DVS or SpyGlass DS will be performed post ERCP for direct viewing of the bile ducts. What is seen during the procedure will determine a course of treatment. Among the options are biopsies taken, stones treated/removed, or a stent placed

Other indications

ERCP (Endoscopic Retrograde Cholangiopancreatography)

Intervention Type PROCEDURE

ERCP procedure will be performed to visualize bile ducts.

SpyGlass DVS and SpyGlass Digital Simple (DS)

Intervention Type DEVICE

Cholangioscopy using SpyGlass™ DVS or SpyGlass DS will be performed post ERCP for direct viewing of the bile ducts. What is seen during the procedure will determine a course of treatment. Among the options are biopsies taken, stones treated/removed, or a stent placed

Interventions

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ERCP (Endoscopic Retrograde Cholangiopancreatography)

ERCP procedure will be performed to visualize bile ducts.

Intervention Type PROCEDURE

SpyGlass DVS and SpyGlass Digital Simple (DS)

Cholangioscopy using SpyGlass™ DVS or SpyGlass DS will be performed post ERCP for direct viewing of the bile ducts. What is seen during the procedure will determine a course of treatment. Among the options are biopsies taken, stones treated/removed, or a stent placed

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age 18 or older.
* Willing and able to provide written informed consent to participate in the study.
* Willing and able to comply with the study procedures.
* Indicated for ERCP and cholangioscopy or indicated for ERCP with suspected need for cholangioscopy.

Exclusion Criteria

* Endoscopic techniques are contraindicated.
* ERCP is contraindicated
* A medical condition that warrants the use of the device outside of the indication for use.
* Requirement for anticoagulation that cannot be safely stopped at least 7 days prior to the procedure.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Benedict Devereaux

Role: PRINCIPAL_INVESTIGATOR

Royal Brisbane and Women's Hospital

James Lau

Role: PRINCIPAL_INVESTIGATOR

Prince of Wales Hospital

Randhir Sud

Role: PRINCIPAL_INVESTIGATOR

Institute of Digestive & Hepatobiliary Sciences

Saad Niaz

Role: PRINCIPAL_INVESTIGATOR

Civil Hospital Karachi

Abdulrahman Aljebreen

Role: PRINCIPAL_INVESTIGATOR

King Khalid University Hospital

Ang Tiing Leong

Role: PRINCIPAL_INVESTIGATOR

Changi General Hospital Pte Ltd.

Jorg Reichenberger

Role: PRINCIPAL_INVESTIGATOR

Netcare Unitas Hospital

Jong Moon

Role: PRINCIPAL_INVESTIGATOR

Soon Chun Hyang University

Rungsun Rerknimitr

Role: PRINCIPAL_INVESTIGATOR

King Chulalongkorn Memorial Hospital

Ichiro Yasuda

Role: PRINCIPAL_INVESTIGATOR

Teikyo University Mizonokuchi Hospital

Arthur J. Kaffes

Role: PRINCIPAL_INVESTIGATOR

Royal Prince Alfred Hospital, Sydney, Australia

Nam Q. Nguyen

Role: PRINCIPAL_INVESTIGATOR

Royal Adelaide Hospital

Amit Maydeo

Role: PRINCIPAL_INVESTIGATOR

Baldota Institute of Digestive Sciences

Mohan Ramchandani

Role: PRINCIPAL_INVESTIGATOR

Asian Institute of Gastroenterology

Mahesh Goenka

Role: PRINCIPAL_INVESTIGATOR

Apollo Gleneagles Hospital

Professor R. Kochhar

Role: PRINCIPAL_INVESTIGATOR

Postgraduate Institute of Medical Education & Research

Takao Itoi

Role: PRINCIPAL_INVESTIGATOR

Tokyo Medical University

Masayuki Kitano

Role: PRINCIPAL_INVESTIGATOR

Kinki University School of Medicine

Jong K. Lee

Role: PRINCIPAL_INVESTIGATOR

Samsung Medical Center

Dongwan Seo

Role: PRINCIPAL_INVESTIGATOR

Asan Medical Center

Locations

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Royal Brisbane and Women's Hospital

Herston, Queensland, Australia

Site Status

Royal Adelaide Hospital

Adelaide, , Australia

Site Status

Royal Prince Alfred Hospital

Newtown, , Australia

Site Status

Prince of Wales Hospital

Shatin, , Hong Kong

Site Status

Apollo Gleneagles Hospitals Kolkata

Kolkata, West Bengal, India

Site Status

Postgraduate Institute of Medical Education & Research

Chandigarh, , India

Site Status

Medanta -The Medicity Institute of Digestive & Hepatobiliary Sciences

Gurgaon, , India

Site Status

Asian Institute of Gastroenterology

Hyderabad, , India

Site Status

Baldota Institute of Digestive Sciences

Pārel, , India

Site Status

Teikyo University Mizonokuchi Hospital

Kawasaki, , Japan

Site Status

Kinki University School of Medicine

Ōsaka-sayama, , Japan

Site Status

Tokyo Medical University

Tokyo, , Japan

Site Status

Civil Hospital- Karachi

Karachi, , Pakistan

Site Status

King Khalid University Hospital

Riyadh, , Saudi Arabia

Site Status

Changi General Hospital Pte Ltd.

Singapore, , Singapore

Site Status

Netcare Unitas Hospital

Centurion, , South Africa

Site Status

Soon Chun Hyang University Bucheon Hospital

Bucheon-si, , South Korea

Site Status

Asan Medical Center

Seoul, , South Korea

Site Status

Samsung Medical Center

Seoul, , South Korea

Site Status

King Chulalongkorn Memorial Hospital

Bangkok, , Thailand

Site Status

Countries

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Australia Hong Kong India Japan Pakistan Saudi Arabia Singapore South Africa South Korea Thailand

References

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Maydeo AP, Rerknimitr R, Lau JY, Aljebreen A, Niaz SK, Itoi T, Ang TL, Reichenberger J, Seo DW, Ramchandani MK, Devereaux BM, Lee JK, Goenka MK, Sud R, Nguyen NQ, Kochhar R, Peetermans J, Goswamy PG, Rousseau M, Bhandari SP, Angsuwatcharakon P, Tang RSY, Teoh AYB, Almadi M, Lee YN, Moon JH; SpyGlass AMEA Registry Group. Cholangioscopy-guided lithotripsy for difficult bile duct stone clearance in a single session of ERCP: results from a large multinational registry demonstrate high success rates. Endoscopy. 2019 Oct;51(10):922-929. doi: 10.1055/a-0942-9336. Epub 2019 Jun 27.

Reference Type DERIVED
PMID: 31250408 (View on PubMed)

Other Identifiers

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90947376

Identifier Type: -

Identifier Source: org_study_id

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