Improving Shared-Decision Making in the Intensive Care Unit Using Patient-reported Outcome Information

NCT ID: NCT05155150

Last Updated: 2023-04-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

160 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-09

Study Completion Date

2024-05-31

Brief Summary

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The aim of this study is to evaluate the effect of incorporation of outcome information in the Intensive Care Unit (ICU) decision-making process on patient and family reported outcomes and experiences of patients, relatives and ICU clinicians in a randomized clinical trial design in the Jeroen Bosch Ziekenhuis and Radboudumc in the Netherlands.

Detailed Description

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Background Due to advances in critical care medicine, more patients survive their critical illness. However, many Intensive Care Unit (ICU) survivors suffer from physical, cognitive and/or mental problems impacting patients' quality of life (QoL). Because of a lack of long-term outcome information, ICU physicians make decisions regarding ICU treatment based on their clinical experience and intuition. Moreover, patients and relatives are often not involved in the decision-making process.

To improve the ICU decision-making process and to make it more substantiated, the use of patient-reported outcome measures (PROMs) is of utmost importance. Therefore, the Radboudumc, in collaboration with six regional hospitals, including Jeroen Bosch Ziekenhuis (JBZ), set up a large-scale prospective cohort study, MONITOR-IC (www.monitor-ic.nl), to study long-term outcomes of ICU survivors', their QoL and their needs.

This research sets out to evaluate the effect of incorporation of outcome information in the ICU decision-making process on patient and family reported outcomes and experiences of patients, relatives and ICU clinicians in a randomized clinical trial design in the Jeroen Bosch Ziekenhuis and Radboudumc in the Netherlands.

Methods A prediction model for long-term QoL was previously developed using physiological, pathological, drug and treatment data from patients' electronic health record combined with PROMs from one centre of the MONITOR-IC. It was externally validated with the data of six other centres and an E-health tool was developed, incorporating this prediction model. For this research, the E-health tool will be incorporated in family meetings.

Conditions

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Intensive Care Unit Syndrome Patient Engagement

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized trial
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Intervention group

Providing patient-reported outcome: patients receive personalized information on expected quality of life one year after ICU during ICU admission (during a family meeting)

Group Type EXPERIMENTAL

Providing patient-reported outcome

Intervention Type BEHAVIORAL

Patients receive personalized information on expected quality of life one year after ICU during ICU admission (during a family meeting)

Control group

Family meetings take place as usual.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Providing patient-reported outcome

Patients receive personalized information on expected quality of life one year after ICU during ICU admission (during a family meeting)

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Patients admitted to the ICU for 12 hours or more
* Patients (or their legal representative) provide written informed consent

Exclusion Criteria

* Patients admitted to the ICU due to a COVID-19 infection
* Moribund patients
Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Jeroen Bosch Ziekenhuis

OTHER

Sponsor Role collaborator

Radboud University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Marieke Zegers

PhD and Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marieke Zegers, PhD

Role: PRINCIPAL_INVESTIGATOR

Intensive Care, Radboud university medical center

Koen Simons, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Intensive Care, Jeroen Bosch Ziekenhuis

Mark Van den Boogaard, PhD

Role: PRINCIPAL_INVESTIGATOR

Intensive Care, Radboud university medical center

Locations

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Radboud university medical centre

Nijmegen, Gelderland, Netherlands

Site Status RECRUITING

Jeroen Bosch Ziekenhuis

's-Hertogenbosch, North Brabant, Netherlands

Site Status RECRUITING

Countries

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Netherlands

Central Contacts

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Marieke Zegers, PhD

Role: CONTACT

0031243619269

Mark van den Boogaard, PhD

Role: CONTACT

Facility Contacts

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Marieke Zegers, PhD

Role: primary

0031243619269

Mark van den Boogaard, PhD

Role: backup

Koen Simons, MD, PhD

Role: primary

References

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Porter LL, Simons KS, van der Hoeven JG, van den Boogaard M, Zegers M. Discussing expected long-term quality of life in the ICU: effect on experiences and outcomes of patients, family, and clinicians-a randomized clinical trial. Intensive Care Med. 2025 Mar;51(3):478-489. doi: 10.1007/s00134-025-07812-5. Epub 2025 Feb 24.

Reference Type DERIVED
PMID: 39992444 (View on PubMed)

Other Identifiers

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112002

Identifier Type: -

Identifier Source: org_study_id

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