MDD(Mild Cognitive Impairment Delirium Dementia) Cohort

NCT ID: NCT05113446

Last Updated: 2022-08-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

163 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-01

Study Completion Date

2025-12-31

Brief Summary

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* Identify the degree of delirium in subjects with mild cognitive impairment and find the risk factors of delirium. Mortality, hospital stay, and medical expenses are analyzed as clinical consequences related to delirium incidence.
* Dementia conversion rate and conversion period of subjects with mild cognitive impairment with delirium and it identifies the effect of delirium on dementia conversion.
* Develop an AI(Artificial intelligence) algorithm for predicting dementia transition in subjects with mild cognitive impairment based on the research results of the 1st, 2nd, and 3rd years.

Detailed Description

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Conditions

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Delirium Mild Cognitive Impairment Dementia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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MCI(Mild Cognitive Impairment) group

* Inclusion criteria : Patients 65 years of age or older who are admitted to a LTC(long-term care) facilities, Patients diagnosed with mild cognitive impairment by doctors, Patients with a score of 18 or more and 23 or less on the Mini-Mental State Examination
* Exclusion criteria : Patients unable to measure the delirium assessment tool, The Short Confusion Assessment Methods (S-CAM) (Inouye, 2014) due to severe vision and hearing problems, Patients with serious psychiatric or neurological diagnosis,Patients who died or were transferred on the day of admission, Patients receiving emergency treatment at the time of the delirium assessment or unable to measure or intervene with S-CAM due to hospital circumstances

Delirium assessment using S-CAM

Intervention Type DIAGNOSTIC_TEST

Twice a day, the rounds of nurses in shifts, 8:00 am - 10:00 am, 4:00 pm - 6:00 pm Trained research assistants assessed delirium using S-CAM

Interventions

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Delirium assessment using S-CAM

Twice a day, the rounds of nurses in shifts, 8:00 am - 10:00 am, 4:00 pm - 6:00 pm Trained research assistants assessed delirium using S-CAM

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients 65 years of age or older who are admitted to a LTC
* Patients diagnosed with mild cognitive impairment by doctors
* Patients with a score of 18 or more and 23 or less on the Mini-Mental State Examination

Exclusion Criteria

* Patients unable to measure the delirium assessment tool, The Short Confusion Assessment Methods (S-CAM) (Inouye, 2014) due to severe vision and hearing problems
* Patients with serious psychiatric or neurological diagnosis,Patients who expire or were transferred on the day of admission -
* Patients receiving emergency treatment at the time of the delirium assessment or unable to measure or intervene with S-CAM due to hospital circumstances
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Keimyung University Dongsan Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Kyoung ja Moon

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Yangsan Seoul long-term care (LTC) facilities

Daegu, Gyeongsangnam-do, South Korea

Site Status RECRUITING

Gunsan Chamsarang long-term care (LTC) facilities

Daegu, Jeollabuk-do, South Korea

Site Status NOT_YET_RECRUITING

Countries

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South Korea

Central Contacts

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Kyoung ja Moon, doctor

Role: CONTACT

+821023026302

min a Park

Role: CONTACT

+821023026302

Facility Contacts

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YooJeong Yang

Role: primary

821054258230

Hyeonsuk An

Role: primary

+821020788428

References

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Moon KJ, Park M. Protocol for a prospective, longitudinal cohort study on the incidence of dementia after the onset of delirium in patients with mild cognitive impairment: MDDCohort (Mild Cognitive Impairment Delirium Dementia). BMC Geriatr. 2024 Nov 7;24(1):922. doi: 10.1186/s12877-024-05480-6.

Reference Type DERIVED
PMID: 39511473 (View on PubMed)

Other Identifiers

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2019R1I1A3A0106056112

Identifier Type: -

Identifier Source: org_study_id

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