Alzheimer's Disease and Related Disorders

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

700 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-11-30

Study Completion Date

2017-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to compare characteristics of gait and balance measured among patients with Alzheimer's disease or related disorders separated into 3 groups according to the stage of disease (i.e., pre-dementia, mild and moderate dementia stages); to determine the effects of anti-dementia drugs and vitamin D on cognitive motor abnormalities; and to establish a database at Angers University Memory Centre.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Pre-demential Motoric Cognitive Risk Syndrome in Ageing Subjects

NCT05640141

Motoric Cognitive Risk Syndrome Mild Cognitive Impairment Alzheimer Disease +1 more

UNKNOWN

Predictive Value of Cognitive Tests Performed for the Diagnosis of Alzheimer's Disease and Related Disorders

NCT01316562

Alzheimer's Disease Impaired Cognition Memory Disorders

UNKNOWN

Contribution of Physical Activity to Self-esteem and Motivation in Older Adults With Minor to Major Cognitive Disorders Such as Alzheimer's Disease or Related Disorders

NCT03866018

Cognitive Disorders

UNKNOWN NA

Patients With Alzheimer's Disease or Related Youth Disease

NCT03508024

Alzheimer Disease, Early Onset Lewy Body Disease Frontotemporal Lobar Degeneration

COMPLETED

Impact of Controlling Vascular Risk Factors on the Progression of Alzheimer's Disease

NCT01423396

Alzheimer's Disease Cardiovascular Risk Factors

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Although gait disorders are frequently associated with Alzheimer's disease and related disorders (ADRD), few studies have focused on cognitive motor effects of anti-dementia drugs and vitamin D.

The objectives of this study are to

* Compare characteristics of gait and balance measured among patients with ADRD separated into 3 groups according to stages of disease (i.e., pre-dementia, mild and moderate dementia stages)
* To determine the effects of anti-dementia drugs and vitamin D on cognitive motor abnormalities
* To determine whether motor abnormalities could be associated with cognitive impairments, specifically executive dysfunctions
* To establish a database at Angers University Memory Center.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Alzheimer's Disease Gait Apraxia Impaired Cognition

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group 1

Patients with Mild Cognitive Impairment

Drug intervention

Intervention Type DRUG

before-after interventional (anti-dementia drugs and/or vitamin D) study

Group 2

Patients with Mild Alzheimer's disease or related disorders

Drug intervention

Intervention Type DRUG

before-after interventional (anti-dementia drugs and/or vitamin D) study

Group 3

Patients with Moderate Alzheimer's disease or related disorders

Drug intervention

Intervention Type DRUG

before-after interventional (anti-dementia drugs and/or vitamin D) study

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Drug intervention

before-after interventional (anti-dementia drugs and/or vitamin D) study

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Anti-dementia drugs and/or vitamin D

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* All elderly patients from the University Memory Center of Angers University Hospital.
* Able to walk without any walking aid on 15 meters
* Mini-Mental Status Examination score \> 10
* Being affiliated to a social security regime

Exclusion Criteria

* Mini-Mental Status Examination score ≤ 10
* Subject suffering from pre-existing impellent disturbances
* History of cerebrovascular accident or other cerebro-spinal pathology
* Poor workmanship of the written or oral French language
* Use of walking aid such as walking frame with wheels or tricycle.
* Acute medical or surgical disease in the past 3 months
* Refusal to participate (or trustworthy person)
* Near visual acuity \< 2/10

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes