Cognitive Rehabilitation in Alzheimer's Disease

NCT ID: NCT02247180

Last Updated: 2014-09-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-09-30

Study Completion Date

2015-12-31

Brief Summary

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This study aims to proof the efficacy of a cognitive rehabilitation program for patients with mild dementia in Alzheimers Disease with respect to activities of daily living.

Detailed Description

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This prospective randomized, single blind intervention study aims to proof a cognitive rehabilitation program for patients with mild dementia in Alzheimers Disease (AD). The investigators modified a manualized and established German behavioural therapy program (KORDIAL) to use in a group context. The respective modules contain multimodal and multiprofessional approaches to improve capabilities relevant to activities of daily living (external memory support, compensation strategies, training of everyday competence, communication training). The intervention group receives this therapy for 12 weeks. Age and gender matched participants with AD serve as active control sample receiving a standardized cognitive training in the domesticity. The primary outcome are measurements of skills in activities of daily living prior the intervention as well as at the end of the intervention (after 3 months) and after 6 months (Follow up).

Conditions

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Alzheimer's Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Cognitive Rehabilitation

cognitive rehabilitation for 12 weeks

Group Type EXPERIMENTAL

cognitive rehabilitation

Intervention Type BEHAVIORAL

Cognitive Training

standardized cognitive training in the domesticity

Group Type ACTIVE_COMPARATOR

standardized cognitive training

Intervention Type BEHAVIORAL

Interventions

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cognitive rehabilitation

Intervention Type BEHAVIORAL

standardized cognitive training

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* mild dementia in Alzheimer's disease (NINCDS-ADRDA)
* Mini Mental State ≥ 17

Exclusion Criteria

* severe psychiatric disorder
* severe brain disorder (epilepsy, tumor, stroke)
* contraindication for MRI examination
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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German Center for Neurodegenerative Diseases (DZNE)

OTHER

Sponsor Role collaborator

University of Rostock

OTHER

Sponsor Role lead

Responsible Party

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Elisabeth Kasper

Dipl. psych

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Stefan Teipel, Prof.

Role: PRINCIPAL_INVESTIGATOR

Department of Psychosomatic Medicine, University of Rostock, Rostock, Germany

Locations

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Department of Psychosomatic Medicine, University of Rostock

Rostock, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Elisabeth Kasper

Role: CONTACT

+49 0381 4949618

Yvonne Schmidt

Role: CONTACT

+49 0381 4949471

Facility Contacts

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Elisabeth Kasper

Role: primary

+49 381 4949618

Other Identifiers

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A 2014-0113

Identifier Type: -

Identifier Source: org_study_id

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