Predictive Factors for Initial MMSE Score and Rapid Decline in Alzheimer's Disease Patients

NCT ID: NCT07122856

Last Updated: 2025-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-09-15

Study Completion Date

2026-03-15

Brief Summary

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This study looks at people with Alzheimer's disease to find out which factors are linked to their initial score on the Mini-Mental State Examination (MMSE) and which factors may predict a fast decline in their score over 12 months. Researchers will review medical records from patients seen at the Memory Clinic of Gonesse Hospital and analyze information such as age, education, medical history, nutrition, mood, and caregiver burden. The goal is to better understand what influences early cognitive performance and how quickly it changes, to help improve patient care and planning.

Detailed Description

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Conditions

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Alzheimer Disease Mini-Mental State Examination Cognitive Dysfunction Neuropsychological Tests Caregivers

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Confirmed diagnosis of Alzheimer's disease according to NIAA 2018 or IWG 2021 criteria
* At least two MMSE evaluations spaced 12 months apart
* Follow-up at the Memory Clinic of CH Gonesse

Exclusion Criteria

* Presence of other neurodegenerative diseases (e.g., Frontotemporal Dementia, Multiple System Atrophy, Vascular Dementia, LATE)
* Patient has moved out of the study area (outside the CH Gonesse territory)
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier de Gonesse

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Centre Hospitalier de Gonesse

Gonesse, France, France

Site Status

Countries

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France

Facility Contacts

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Abdullah Blakime

Role: primary

01.34.53.24.64

Other Identifiers

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0114_NEUROLOGIE_TARGET MMSE

Identifier Type: -

Identifier Source: org_study_id

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