Prevalence of Dementia and Delirium in Outpatient Clinics (DESTAN Trial)

NCT ID: NCT04973709

Last Updated: 2022-10-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

714 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-05

Study Completion Date

2025-11-11

Brief Summary

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The aim of this study is to assess the prevalence and etiologic risk factors of delirium in outpatient geriatric patients and also hospitalized patients.

Detailed Description

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This study aimed to investigate the frequency of delirium and examines the association between delirium and other possible risk factors and prognostic factors (dementia etc.)

Conditions

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Delirium in Old Age Delirium Superimposed on Dementia Delirium With Dementia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Delirium with dementia

Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.

Confussion assessment method (CAM)

Intervention Type DIAGNOSTIC_TEST

Participants enrolled in the Delirium group according to the CAM.

Dementia diagnosis

Intervention Type DIAGNOSTIC_TEST

Participants enrolled in the Dementia group according to the CDR scores and MMSE scores and DSM4/5 criteria

Dementia without Delirium

Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.

Dementia diagnosis

Intervention Type DIAGNOSTIC_TEST

Participants enrolled in the Dementia group according to the CDR scores and MMSE scores and DSM4/5 criteria

Delirium without Dementia

Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.

Confussion assessment method (CAM)

Intervention Type DIAGNOSTIC_TEST

Participants enrolled in the Delirium group according to the CAM.

No dementia, No delirium

Delirium was detected using the short form of the Confusion Assessment Method (CAM) both at admission and daily throughout the hospital stay. Cognitive status was determined using the Mini-Mental State Exam, Clinical Dementia Rating (CDR). Dementia was defined by a CDR score of 1. The primary independent variable was a composite of delirium and dementia diagnosis, and we examined the overlap by categorizing the cases into four groups: no delirium or dementia, dementia alone, delirium alone, and DSD.

No interventions assigned to this group

Interventions

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Confussion assessment method (CAM)

Participants enrolled in the Delirium group according to the CAM.

Intervention Type DIAGNOSTIC_TEST

Dementia diagnosis

Participants enrolled in the Dementia group according to the CDR scores and MMSE scores and DSM4/5 criteria

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* We included all 65 years older patients who evaluated according to a comprehensive geriatric assessment that is consistently performed during admission to the outpatients' clinic of the hospital.
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Gulhane Training and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Bilal Katipoglu

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mehmet Naharcı

Role: PRINCIPAL_INVESTIGATOR

Saglik Bilimleri Universitesi

Locations

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Gulhane training and research hospital

Ankara, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Bilal Katipoglu, MD

Role: CONTACT

+905543330380

Facility Contacts

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Bilal Katipoglu, MD

Role: primary

+905543330380

References

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Katipoglu B, Demircan SK, Naharci MI. Association of drug burden index with delirium in community-dwelling older adults with dementia: a longitudinal observational study. Int J Clin Pharm. 2023 Oct;45(5):1267-1276. doi: 10.1007/s11096-023-01551-7. Epub 2023 Mar 18.

Reference Type DERIVED
PMID: 36933080 (View on PubMed)

Other Identifiers

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2020-382

Identifier Type: -

Identifier Source: org_study_id

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