Natural History and Patient Journey in Dementia: a Nationwide Linked Electronic Health Records Study of 5.6 Million Individuals.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

4309481 participants

Study Classification

OBSERVATIONAL

Study Start Date

1998-01-01

Study Completion Date

2020-11-30

Brief Summary

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The trajectory of dementia patients within the national health system and their recent temporal trends remains to be fully elucidated. To study the dementia incidence, mortality and case-fatality, we implemented a longitudinal cohort study with the linked electronic health records of 5.6 million population in the UK from 1998 to 2016 (CALIBER). A matched case-control study design was used to investigate the causes of hospitalization and death comparing individuals with and without incident dementia.

Detailed Description

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Conditions

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Dementia, Alzheimer, Electronic Health Records, Hospitalizations, Epidemiology, Comorbidity, United Kingdom, Incidence, Mortality, Cause of Death

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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The study does not have an intervention, but observe the dementia incidence of the UK disease-free population.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* We identify individuals aged 30 years or older and registered in the current primary care practice for at least one year.

Exclusion Criteria

* Individuals are excluded if they had a prior history of dementia before study entry.

Minimum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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ISAC18_228

Identifier Type: -

Identifier Source: org_study_id