Post Market Clinical Follow up Study With the Cervical Disc Prothesis MOVE®-C

NCT ID: NCT05035693

Last Updated: 2024-11-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

170 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-11

Study Completion Date

2027-03-11

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Study design: International, prospective, multicentre, non-randomised, observational study according to § 23b MPG.

Objectives: Observational study to confirm the safety and performance of the cervical disc prosthesis MOVE®-C.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This clinical investigation is conducted to gain post market results on the Cervical Disc Prosthesis MOVE®-C and to demonstrate the safety and performance. Besides, it is aimed to gain knowledge concerning the development of patients' quality of life (QoL) after the implantation of the Cervical Disc Prosthesis MOVE®-C and to collect data for the analysis of the range of motion (ROM), which is an essential parameter for motion-preserving implants.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Discopathy Herniated Cervical Disc Stenoses, Spinal Radiculopathy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PMCF MOVE-C

PMCF MOVE®\_C is a single arm observational study with 170 patients.

Group Type EXPERIMENTAL

MOVE®-C

Intervention Type DEVICE

Momo- or bisegmental implantation of MOVE®-C cervical prothesis.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

MOVE®-C

Momo- or bisegmental implantation of MOVE®-C cervical prothesis.

Intervention Type DEVICE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

cervical disc prothesis

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Diagnosis of discopathy or disc hernia with radiculopathy or stenosis of the foramen and spinal canal,
2. documented individual history of neck and/or upper extremity pain and/or functional/neurological deficit associated with the cervical level to be treated,
3. no surgical treatment regarding the planned index surgery within the last six weeks prior implantation,
4. unsuccessful conservative medical care regarding the indication within the last six weeks,
5. age ≥18 years,
6. patient must agree to fully participate in the clinical trial and give informed consent in writing,
7. patient is capable to realise the nature, aims and possible consequences of the clinical trial (MPG §20.2.1),
8. patient information has been provided and all written consents of the patient are available.

Exclusion Criteria

* Known contraindication against the use of cervical intervertebral disc prostheses in accordance with the manufacturer's instructions for use:

1. Bone mineral density with T-score ≤ -1.5 as determined by spine DXA if male ≥ 60 years of age or female ≥ 50 years of age,
2. active systemic infection or infection at the operative site,
3. sustained osteoporotic fracture of the spine, hip or wrist,
4. spinal metastases,
5. known allergy to titanium or polycarbonate-urethane,
6. confirmed pregnancy,
7. severe cervical myelopathy,
8. patients requiring a treatment that destabilises the spine (e.g. posterior element decompression),
9. advanced cervical anatomical deformity at the operative site (e.g. ankylosing spondylitis, scoliosis),
10. advanced degenerative changes (e.g. spondylosis) at the index vertebral level,
11. patient is kept in an institution under judicial or official orders (MPG §20.3).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

NGMedical GmbH

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Olaf Süss, PD Dr. med.

Role: PRINCIPAL_INVESTIGATOR

DRK Kliniken Berlin

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Wiener Gesundheitsverbund-Klinik Penzing

Vienna, , Austria

Site Status RECRUITING

DRK Klinikum Berlin

Berlin, , Germany

Site Status RECRUITING

Wirbelsäulenzentrum Fulda Main, Kinzig

Gelnhausen, , Germany

Site Status RECRUITING

Medizinisches Versorgungszentrum Steinburg

Itzehoe, , Germany

Site Status RECRUITING

Katholisches Klinikum Koblenz - Montabaur

Koblenz, , Germany

Site Status RECRUITING

Neurochirurgie am Gasteig

München, , Germany

Site Status RECRUITING

Rhein-Maas Klinikum Würselen

Würselen, , Germany

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Austria Germany

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Saskia Mathieu, M.Sc.

Role: CONTACT

+49687399997118

Nino Weiland, B.Sc.

Role: CONTACT

+49687399997104

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Ronald Sabitzer, OA

Role: primary

0043 6767017974

Olaf Süss, PD Dr.med.

Role: primary

+493030354260

Sven Mularski, Dr.med.

Role: backup

+493030354260

Bernd Hölper, Dr. med.

Role: primary

Yasmin Mitsikari

Role: backup

Ardeshir Ardeshiri, Dr. med.

Role: primary

0049- 821-7726702

Lisa-Marie Feldhaus

Role: backup

0049- 821-7726702

Francis K Kilian, Dr.med.

Role: primary

0049 261 496-6457

Nina Schroeder

Role: backup

0049 261 496-6457

Ardavan Ardeshiri, Dr. med.

Role: primary

0049 896666339040

Jenifer Kilian

Role: backup

0049 896666339040

Rolf Sobottke, Prof.Dr.med.

Role: primary

0049 2405623372

Khaled Allan

Role: backup

0049-2405-62-8258

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

DRKS00022971

Identifier Type: OTHER

Identifier Source: secondary_id

P004

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

M6-C Post Approval Study (PAS)
NCT04122248 ACTIVE_NOT_RECRUITING
PMCF Neo Pedicle Screw and Cage Systems
NCT03956537 ACTIVE_NOT_RECRUITING
PCM Cervical Disc System
NCT00578812 COMPLETED PHASE3