Relationship of Retinal and Visual Cortex Structure and Visual Acuity After Congenital Cataract Surgery
NCT ID: NCT04976608
Last Updated: 2021-07-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
30 participants
OBSERVATIONAL
2021-06-16
2021-12-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Study Groups
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Group 1
The BCVA of eyes is greater than 0.6
No interventions assigned to this group
Group 2
The BCVA of eyes is from 0.1 to 0.6
No interventions assigned to this group
Group 3
The BCVA of eyes is less than 0.6
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Congenital cataract surgery is planned
* The operation was successful without any complications
* Can cooperate well with OCT and MRI examinations
Exclusion Criteria
* Behavioral, cognitive impairment
* Developmental delay
4 Years
60 Years
ALL
No
Sponsors
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Wenzhou Medical University
OTHER
Responsible Party
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Yune Zhao
Vice president of Eye Hospital of Wenzhou Medical University
Principal Investigators
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Yune Zhao
Role: STUDY_DIRECTOR
Ophthalmology and Optometry Hospital
Locations
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Eye Hospital of Wenzhou Medical College
Wenzhou, Zhejiang, China
Countries
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Central Contacts
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Facility Contacts
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References
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Lu L, Li Q, Zhang L, Tang S, Yang X, Liu L, Sweeney JA, Gong Q, Huang X. Altered cortical morphology of visual cortex in adults with monocular amblyopia. J Magn Reson Imaging. 2019 Nov;50(5):1405-1412. doi: 10.1002/jmri.26708. Epub 2019 Mar 10.
Allen B, Schmitt MA, Kushner BJ, Rokers B. Retinothalamic White Matter Abnormalities in Amblyopia. Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):921-929. doi: 10.1167/iovs.17-22930.
Long E, Zhang X, Liu Z, Wu X, Tan X, Lin D, Cao Q, Chen J, Lin Z, Wang D, Li X, Li J, Wang J, Li W, Lin H, Chen W, Liu Y. Dynamic response to initial stage blindness in visual system development. Clin Sci (Lond). 2017 Jun 28;131(13):1515-1527. doi: 10.1042/CS20170234. Print 2017 Jul 1.
Other Identifiers
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amblyopia-LZL
Identifier Type: -
Identifier Source: org_study_id
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