Postural Control During Concurrent Cognitive Tasks During Optic Flow Stimulation
NCT ID: NCT05117463
Last Updated: 2024-08-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
72 participants
OBSERVATIONAL
2022-07-01
2025-02-28
Brief Summary
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Detailed Description
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Optic flow (OF) has been used to study the effect of visual input on balance control. Most of the studies displayed OF on a screen rather than using 360 degrees visual field environment. Therefore, the subjects could obtain reference inputs for balance adjustment. The new VR headset makes it possible to play OF in a 360-degree visual field in which the subject will not able to obtain any reference inputs rather than using somatosensory and/or vestibular systems. It is unclear how the effect of aging and attention relocation affects postural control with concurrent visual and auditory attention tasks. In this study, fNIRS will be used to detect the brain activity of healthy adults in the prefrontal and temporal-parietal junction as they complete concurrent cognitive and visual tasks displayed by a VR headset. This work will focus on age and test positions (sitting vs standing). As age can play a role in brain activation levels, the investigators will compare results among younger adults (25-35 years), older adults (65-85 years), and older adults with the risk of falls. All the subjects will undergo concurrent auditory reaction time tasks and visual tracking tasks. The investigators will compare the brain images from the test conditions between the age groups and investigate if brain activity differs during the performance of reaction time tasks and visual tacking tasks. The goal of this study is to examine the effect of concurrent visual and auditory tasks on brain activation and postural control.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Healthy Younger Adults
Healthy younger adults without any neurological and orthopedic disorders.
Optic Flow Stimulation
The optic flow will be displayed at different speeds. The subject will need to look at the center of the optic flow.
Auditory Reaction Time
Two different pitches of tones will be played. The participants will need to press a button on the right or left hand based on the pitch of the tone.
Healthy Older Adults
Healthy older adults without any neurological and orthopedic disorders.
Optic Flow Stimulation
The optic flow will be displayed at different speeds. The subject will need to look at the center of the optic flow.
Auditory Reaction Time
Two different pitches of tones will be played. The participants will need to press a button on the right or left hand based on the pitch of the tone.
Older Adults with higher risk of falls
Older adults with a history of falls or poor balance based on the clinical balance and gait assessment.
Optic Flow Stimulation
The optic flow will be displayed at different speeds. The subject will need to look at the center of the optic flow.
Auditory Reaction Time
Two different pitches of tones will be played. The participants will need to press a button on the right or left hand based on the pitch of the tone.
Interventions
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Optic Flow Stimulation
The optic flow will be displayed at different speeds. The subject will need to look at the center of the optic flow.
Auditory Reaction Time
Two different pitches of tones will be played. The participants will need to press a button on the right or left hand based on the pitch of the tone.
Eligibility Criteria
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Inclusion Criteria
* Right-handed
Exclusion Criteria
* Fall risk group: other medical issues rather than balance problems
25 Years
85 Years
ALL
Yes
Sponsors
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National Institute on Aging (NIA)
NIH
Chia-Cheng Lin, PhD, PT, MSPT
OTHER
Responsible Party
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Chia-Cheng Lin, PhD, PT, MSPT
Associate Professor
Principal Investigators
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Brain Sylcott, PhD
Role: PRINCIPAL_INVESTIGATOR
East Carolina University
Locations
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East Carolina University
Greenville, North Carolina, United States
Countries
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Central Contacts
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Facility Contacts
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References
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Hinderaker M, Sylcott B, Williams K, Lin CC. Aging Affects the Ability to Process the Optic Flow Stimulations: A Functional Near-Infrared Spectrometry Study. J Mot Behav. 2020;52(4):466-473. doi: 10.1080/00222895.2019.1645639. Epub 2019 Jul 30.
Berard JR, Fung J, McFadyen BJ, Lamontagne A. Aging affects the ability to use optic flow in the control of heading during locomotion. Exp Brain Res. 2009 Apr;194(2):183-90. doi: 10.1007/s00221-008-1685-1. Epub 2009 Jan 13.
Dijkstra BW, Bekkers EMJ, Gilat M, de Rond V, Hardwick RM, Nieuwboer A. Functional neuroimaging of human postural control: A systematic review with meta-analysis. Neurosci Biobehav Rev. 2020 Aug;115:351-362. doi: 10.1016/j.neubiorev.2020.04.028. Epub 2020 May 11.
Lin CC, Barker JW, Sparto PJ, Furman JM, Huppert TJ. Functional near-infrared spectroscopy (fNIRS) brain imaging of multi-sensory integration during computerized dynamic posturography in middle-aged and older adults. Exp Brain Res. 2017 Apr;235(4):1247-1256. doi: 10.1007/s00221-017-4893-8. Epub 2017 Feb 14.
Hoppes CW, Sparto PJ, Whitney SL, Furman JM, Huppert TJ. Functional near-infrared spectroscopy during optic flow with and without fixation. PLoS One. 2018 Mar 7;13(3):e0193710. doi: 10.1371/journal.pone.0193710. eCollection 2018.
Other Identifiers
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Interventional
Identifier Type: -
Identifier Source: org_study_id
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