Visual Attention and Eye Movements

NCT ID: NCT03298737

Last Updated: 2025-10-10

Basic Information

• Recruitment Status: ENROLLING_BY_INVITATION
• Total Enrollment: 20 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2017-10-26
• Study Completion Date: 2026-09-01

Brief Summary

The purpose of this study is to provide information about how the brain processes sensory inputs using visual stimuli throughout various psychophysical experiments.

Detailed Description

This laboratory studies visual perception with a focus on the interaction between eye movements and attention. It is well established that attending to a stimulus can profoundly alter perception. For example, attending to a speaker at a crowded party can almost completely filter background both in terms of auditory noise and visual distractions. Although laboratory studies have traditionally investigated the effects of attentional changes in the absence of eye movements, under natural conditions, visual attention is often accompanied by orienting movements to direct our head and eyes towards the relevant objects of interest. Recent work has suggested that these orienting movements affect perception in a manner similar to covert attention. The proposed studies will investigate how eye movements contribute to perception and attention.

The research covered by this protocol combines traditional "button-press" psychophysics with non-invasive eye-tracking to investigate the interaction between eye movements and perception. Subjects will perform simple perceptual tasks, such as judging the orientation or direction of a visual stimulus, while their eye position is monitored with a video eye-tracker. This approach (combining psychophysics and eye-tracking) is flexible, low risk, and fast when compared with neurophysiological studies. However, by focusing on low-level perceptual tasks, the results will be interpretable in the context of larger studies of neurophysiological responses in the visual system.

The investigators hope that this basic research will ultimately have both applied and clinical significance. For example, understanding how perception is influenced by attention and eye-movements in neurotypical populations may provide non-invasive and naturalistic ways to identify and diagnose psychiatric disorders. Additionally, understanding how eye-movements interact with sensory encoding has the potential to improve machine learning algorithms for vision and navigation (These are not a part of the current study, but a potential future impact).

Conditions

Vision, Ocular

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Correct to normal vision population

Covert Spatial Attention

Intervention Type: BEHAVIORAL

During behavioral sessions, subjects will sit in a dark room and view a video monitor placed at the minimum of 57 cm distance away from the subject. Staff will be present throughout all the testing to assist the subject and monitor equipment that is used for tracking their eye position. Subjects will be asked to maintain their heads in a stable position of rest in order to insure accurate tracking of their eye position. To stabilize their head, subjects will either use a "chin rest" in which they position their chin on a soft pad mounted in front of a video screen, or they may use a "bite bar."

Interventions

Covert Spatial Attention

During behavioral sessions, subjects will sit in a dark room and view a video monitor placed at the minimum of 57 cm distance away from the subject. Staff will be present throughout all the testing to assist the subject and monitor equipment that is used for tracking their eye position. Subjects will be asked to maintain their heads in a stable position of rest in order to insure accurate tracking of their eye position. To stabilize their head, subjects will either use a "chin rest" in which they position their chin on a soft pad mounted in front of a video screen, or they may use a "bite bar."

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Age between 18-65
• Corrected-to-normal vision
• No known diagnosis of visual or auditory disorder or impairment

Exclusion Criteria

• Does not have corrected-to-normal vision
• Unable to understand and follow the instructions given of the study
• Known diagnosis of visual or auditory disorder or impairment

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Rochester

OTHER

Sponsor Role: lead

Responsible Party

Jude Mitchell

Assistant Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Brain and Cognitive Sciences, University of Rochester

Rochester, New York, United States

Countries

United States

References

Madelain L, Krauzlis RJ. Pursuit of the ineffable: perceptual and motor reversals during the tracking of apparent motion. J Vis. 2003 Nov 18;3(11):642-53. doi: 10.1167/3.11.1.

Reference Type: BACKGROUND

PMID: 14765950 (View on PubMed)

Other Identifiers

RSRB00068408

Identifier Type: -

Identifier Source: org_study_id