Eye Movement Recordings in the Diagnosis of Traumatic Brain Injury

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

26 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-04-30

Study Completion Date

2014-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The study investigates whether the use of eye movement recordings can provide a reliable diagnostic of previously undiagnosed mild traumatic brain injury (blast and impact) in Operations Enduring Freedom or Iraqi Freedom (OIF/OEF) veterans.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Integrated Eye Tracking and Neural Monitoring for TBI: Optimization

NCT03451058

Traumatic Brain Injury

COMPLETED

Eyetracking and Neurovision Rehabilitation of Oculomotor Dysfunction in Mild Traumatic Brain Injury

NCT03319966

Mild Traumatic Brain Injury Brain Concussion Convergence Insufficiency +3 more

COMPLETED

Oculomotor Assessment of Traumatic Brain Injury (TBI)

NCT03156010

Traumatic Brain Injury

COMPLETED NA

Assessment of Oculomotor, Vestibular and Reaction Time Response Following a Concussive Event

NCT01832714

Concussion, Mild Concussion, Intermediate Concussion, Severe

COMPLETED

Use of Eye Movement Tracking to Detect Oculomotor Abnormality in Traumatic Brain Injury Patients

NCT02776462

Brain Concussion Cerebral Concussion Concussion, Intermediate +5 more

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Eye movements are recorded for Operations Enduring Freedom or Iraqi Freedom (OIF/OEF) veterans with mild traumatic brain injury (mTBI) and compared to the eye movements of those without mTBI. By analyzing and characterizing the differences between the two groups, a diagnostic measure of mTBI through the use of eye movements can be developed.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Traumatic Brain Injury

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control

Control subjects with no Mild Traumatic Brain Injury (MTBI) and no Post-Traumatic Stress Disorder (PTSD)

No interventions assigned to this group

MTBI

Subject with a diagnosis for Mild Traumatic Brain Injury (MTBI)

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* OIF/OEF Veteran;
* Neuropsych diagnosis of MTBI

Exclusion Criteria

* chronically abusing alcohol or illicit drugs.
* uncorrected vision prevents subject from effectively viewing the stimuli, unless they can wear contact lenses during the recording session.
* inability to make normal eye movements (i.e.: saccades, smooth pursuit) required by study paradigms. Note: Deficit can be caused by taking medications that can potentially affect eye movements or any neurological condition that can interfere with making normal eye movement.
* psychological or psychiatric conditions that preclude sustained concentration or ability to perform the tasks.

Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes