Myocardial Perfusion Imaging by Combined 15O-H2O PET and MR

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

73 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-08

Study Completion Date

2022-11-01

Brief Summary

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The trial will include 75 patients with evident or suspected ischemic heart disease refered to Department of Nuclear Medicine \& PET Centre, Aarhus University Hospital, for perfusion imaging by 15O-H2O PET/CT scan of the heart during rest and stress. Instead of the clinical scan participants will undergo perfusion imaging by 15O-H2O PET/MR.

The clinician will receive diagnostic information based on the 15O-H2O PET scan as if the patient had not participated in the study. As such, the study has no influence on the diagnostics or treatments of the patient.

Data from the scans will be used to compare 15O-H2O PET with cardiac MR for evaluation of myocardial perfusion.

Follow up will be done for up to 10 years in regards to major cardiovascular events in order to determine the prognostic value of the scan.

Detailed Description

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Conditions

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Ischemic Heart Disease

Keywords

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Myocardial perfusion imaging Positron-Emission Tomography Cardiac Magnetic Resonance Imaging Coronary Artery Disease Coronary Flow Reserve Myocardial Blood Flow

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Refered for myocardial perfusion imaging by O15-H2O PET at Department of Nuclear Medicine \& PET Centre, Aarhus University Hospital
* \> 18 years of age

Exclusion Criteria

* Allergic to adenosine
* Allergic to gadolinium
* Pregnancy
* Claustrophobia
* Severe Asthma
* Pacemaker or other ferro-magnetic implants
* GFR \< 30

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Locations

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Aarhus University Hospital

Aarhus, Aarhus N, Denmark

Site Status

Countries

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Denmark

Other Identifiers

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PREFER

Identifier Type: -

Identifier Source: org_study_id