Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

115 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-09

Study Completion Date

2021-11-11

Brief Summary

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This study is being done to find out the normal amount of blood within the heart muscle and the variations in this blood flow between a cardiac MRI and TTE.

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Detailed Description

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Conditions

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Healthy Adults

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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Healthy adults

Healthy adults will have blood flow to the heart evaluated using s Real-Time Myocardial Echocardiography (RTMPE) and magnetic resonance image (MRI) to the heart.

Group Type EXPERIMENTAL

Real-Time Myocardial Echocardiography (RTMPE)

Intervention Type DIAGNOSTIC_TEST

Uses sound waves (ultrasound) to produce an images of the heart. During RTMPE a microbubble contrast agent is administered through an intravenous line (IV) to make the images of your heart clearer.

Magnetic resonance image (MRI)

Intervention Type DIAGNOSTIC_TEST

Imaging that focuses on the heart or blood vessels to assess size and function of the heart's chambers, thickness and movement of the walls of the heart, and blood flow in the blood vessels.

Interventions

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Real-Time Myocardial Echocardiography (RTMPE)

Uses sound waves (ultrasound) to produce an images of the heart. During RTMPE a microbubble contrast agent is administered through an intravenous line (IV) to make the images of your heart clearer.

Intervention Type DIAGNOSTIC_TEST

Magnetic resonance image (MRI)

Imaging that focuses on the heart or blood vessels to assess size and function of the heart's chambers, thickness and movement of the walls of the heart, and blood flow in the blood vessels.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years.
* Available for testing performed in Rochester, MN.
* Willing to undergo both an echocardiogram with RTMPE and CMR.
* Study subject providing consent.

Exclusion Criteria

* Adults \< 18 years.
* BMI \<30 kg/m\^2.
* Hypertension.
* Diabetes Mellitus.
* Stroke.
* Cardiomyopathy or structural heart disease.
* Known coronary artery disease or history of myocardial infarction.
* Contraindication to echo enhancement agent or gadolinium administration such as an allergy.
* Renal GFR \< 50 mL/mL.
* Females who are pregnant.
* Subject unwilling to consent.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes