A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease

NCT ID: NCT04464655

Last Updated: 2024-10-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

2130 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-12-12

Study Completion Date

2025-01-31

Brief Summary

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This study aims to identify and assess new CMR techniques that can improve current CMR protocols.

Detailed Description

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The aim of this study is to develop a comprehensive 10-minute protocol based on function and myocardial tissue characterization without the need for contrast injection, which can be standardized for 70% of cardiac patients.

To test this 10-minute CMR protocol for its ability to significantly improve diagnostic decision-making and to reduce cost.

To test its clinical feasibility, performance and cost-effectiveness in different populations including: Non-ischemic cardiomyopathies (-)OS-CMR and Ischemic Heart Disease and CAD (+)OS-CMR

Conditions

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Coronary Artery Disease Myocarditis Infiltrative Cardiomyopathy Dilated Cardiomyopathy Hypertrophic Cardiomyopathy Aortic Valve Stenosis Aortic Valve Regurgitation Pericardial Effusion Congenital Heart Disease Vascular Anomaly

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Healthy Volunteers

Age: \>18 y, No known current or pre-existing medical conditions that would affect the cardiovascular or respiratory system.

No interventions assigned to this group

Patients

Age: \> 18y, Clinically indicated CMR exam

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age: \> 18y, Informed consent No known current or pre-existing significant medical conditions that would affect the cardiovascular or respiratory system


* Age: \>18 y, Informed consent, Clinically indicated CMR exam

Exclusion Criteria

* General MRI contraindications: MR- incompatible devices such as pacemakers, defibrillators, or implanted material or foreign bodies. Consumption of caffeinated drinks or foods (including cocoa and chocolate) during the 12 hours prior to the exam.Regular nicotine consumption during the last 6 months

Patients


* General MRI contraindications: MR- incompatible devices such as pacemakers, defibrillators, or implanted material or foreign bodies Vasoactive medication (e.g. nitro) during the 12 hours prior to the exam. Consumption of caffeinated drinks or foods (including cocoa and chocolate) during the 12 hours prior to the exam.

Regular nicotine consumption during the last 6 months
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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McGill University Health Centre/Research Institute of the McGill University Health Centre

OTHER

Sponsor Role lead

Responsible Party

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Matthias Friedrich

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Matthias G Friedrich, MD

Role: PRINCIPAL_INVESTIGATOR

Research Institute of the McGill University Health Center

Locations

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McGill University Health Center

Montreal, Quebec, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Elizabeth Konidis

Role: CONTACT

514-934-1934 ext. 37305

Adonis Rodaros

Role: CONTACT

514-934-1934 ext. 37305

Facility Contacts

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Matthias G Friedrich, MD

Role: primary

514-934-1934 ext. 62800

Elizabeth Konidis

Role: backup

514-934-1934 ext. 37305

Katerina Eyre, PhD

Role: backup

Other Identifiers

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2020-6128

Identifier Type: -

Identifier Source: org_study_id

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