Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome

NCT ID: NCT00952224

Last Updated: 2009-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

267 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-11-30

Study Completion Date

2009-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In acute myocardial infarction cardiovascular magnetic resonance imaging can retrospectively detect the myocardium at risk and the irreversible injury. This allows for quantifying the extent of salvaged myocardium after reperfusion as a potential strong end point for clinical trials and outcome. The aim of the present study is to determine the prognostic significance and determinants of myocardial salvage assessed by CMR in reperfused ST-elevation myocardial infarction (STEMI).

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

ST-Elevation Myocardial Infarction

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Acute myocardial infarction patients

Patients undergoing primary percutaneous coronary intervention in ST-elevation myocardial infarction plus magnetic resonance imaging

magnetic resonance imaging

Intervention Type OTHER

magnetic resonance imaging is used for prognosis assessment

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

magnetic resonance imaging

magnetic resonance imaging is used for prognosis assessment

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* ST-elevation myocardial infarction \< 12 hours
* primary percutaneous coronary intervention

Exclusion Criteria

* previous myocardial infarction
* prior fibrinolysis
* contraindications to CMR at study entry (such as implanted pacemakers, defibrillators, claustrophobia or metallic intracranial implants)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Leipzig

OTHER

Sponsor Role lead

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Ingo Eitel, MD

Role: PRINCIPAL_INVESTIGATOR

Heart Center Leipzig - University Hospital

Holger Thiele, MD

Role: STUDY_DIRECTOR

Heart Center Leipzig - University Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Leipzig - Heart Center

Leipzig, , Germany

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Germany

References

Explore related publications, articles, or registry entries linked to this study.

Eitel I, Desch S, de Waha S, Fuernau G, Gutberlet M, Schuler G, Thiele H. Long-term prognostic value of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction. Heart. 2011 Dec;97(24):2038-45. doi: 10.1136/heartjnl-2011-300098. Epub 2011 Oct 11.

Reference Type DERIVED
PMID: 21990384 (View on PubMed)

Eitel I, Desch S, Fuernau G, Hildebrand L, Gutberlet M, Schuler G, Thiele H. Prognostic significance and determinants of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction. J Am Coll Cardiol. 2010 Jun 1;55(22):2470-9. doi: 10.1016/j.jacc.2010.01.049.

Reference Type DERIVED
PMID: 20510214 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Leipzig MR 1

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Accelerated Stress CMR in Coronary Artery Disease
NCT05221762 ACTIVE_NOT_RECRUITING
One More Magnetic Resonance Imaging
NCT02293070 COMPLETED NA
CMR Repeatability in STEMI
NCT01468662 COMPLETED