Non-contrast Enhanced Cardiac Magnetic Resonance Normal Values and Imaging Protocols
NCT ID: NCT01728597
Last Updated: 2025-02-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
200 participants
OBSERVATIONAL
2011-12-31
2027-12-31
Brief Summary
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The aim of the present study is the evaluation and optimization of various 1.5 Tesla and 3 Tesla cardiac MR investigation protocols without application of contrast agent as well as the acquisition of normal values for new cardiac MR images techniques:
* normal myocardial morphology: T1-, T2- and T2\*-weighted imaging and acquisition of normal values of magnetic relaxation times (sequence- and protocol dependent),
* normal cardiac function: systolic and diastolic function (sequence- and protocol dependent),
* cardiac anatomy and coronary artery imaging: feasibility to evaluate length, diameter and blood flow (sequence- and protocol dependent),
* normal blood flow topologies in the heart and the surrounding great vessels: 2D- and 3D blood flow imaging and evaluation techniques (sequence- and protocol dependent).
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Detailed Description
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Conditions
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Study Design
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OTHER
OTHER
Study Groups
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healthy volunteers
MR compliant volunteers with no history of cardiovascular diseases
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* ability to give informed consent
Exclusion Criteria
* claustrophobia.
18 Years
80 Years
ALL
Yes
Sponsors
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Amt der Steiermärkischen Landesregierung, Abteilung 3
UNKNOWN
Medical University of Graz
OTHER
Responsible Party
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Ursula Reiter
PhD
Principal Investigators
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Ursula Reiter, PhD
Role: PRINCIPAL_INVESTIGATOR
Medical Unitersity Graz, Department of Radiology, Division of General Radiology
Locations
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Medical Unitersity Graz, Department of Radiology, Division of General Radiology
Graz, Styria, Austria
Countries
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Central Contacts
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Facility Contacts
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References
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Reiter U, Reiter G, Dorr K, Greiser A, Maderthaner R, Fuchsjager M. Normal diastolic and systolic myocardial T1 values at 1.5-T MR imaging: correlations and blood normalization. Radiology. 2014 May;271(2):365-72. doi: 10.1148/radiol.13131225. Epub 2013 Dec 6.
Krauter C, Reiter U, Reiter C, Nizhnikava V, Masana M, Schmidt A, Fuchsjager M, Stollberger R, Reiter G. Automated mitral valve vortex ring extraction from 4D-flow MRI. Magn Reson Med. 2020 Dec;84(6):3396-3408. doi: 10.1002/mrm.28361. Epub 2020 Jun 18.
Reiter C, Reiter U, Krauter C, Nizhnikava V, Greiser A, Scherr D, Schmidt A, Fuchsjager M, Reiter G. Differences in left ventricular and left atrial function assessed during breath-holding and breathing. Eur J Radiol. 2021 Aug;141:109756. doi: 10.1016/j.ejrad.2021.109756. Epub 2021 May 7.
Reiter C, Reiter G, Krauter C, Scherr D, Schmidt A, Fuchsjager M, Reiter U. Evaluation of left ventricular and left atrial volumetric function from native MR multislice 4D flow magnitude data. Eur Radiol. 2024 Feb;34(2):981-993. doi: 10.1007/s00330-023-10017-3. Epub 2023 Aug 15.
Gillette K, Gsell MAF, Prassl AJ, Karabelas E, Reiter U, Reiter G, Grandits T, Payer C, Stern D, Urschler M, Bayer JD, Augustin CM, Neic A, Pock T, Vigmond EJ, Plank G. A Framework for the generation of digital twins of cardiac electrophysiology from clinical 12-leads ECGs. Med Image Anal. 2021 Jul;71:102080. doi: 10.1016/j.media.2021.102080. Epub 2021 Apr 22.
Other Identifiers
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CMR-12-TECH-02
Identifier Type: -
Identifier Source: org_study_id
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