CMR Repeatability in STEMI

NCT ID: NCT01468662

Last Updated: 2014-10-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-11-30

Brief Summary

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The investigators propose to conduct a study to measure the reproducibility of CMR parameters that have been used to predict outcome following PPCI: infarct size, left ventricular volumes, myocardial salvage, microvascular obstruction (MVO) and myocardial oedema.

Detailed Description

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Conditions

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STEMI

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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STEMI

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

Participant may enter study if ALL of the following apply

1. ST segment myocardial infarction as defined by ECG (by 2 contiguous limb leads with \>1 mm ST-segment elevation, or \>2 mm ST-segment elevation in contiguous precordial leads, or new LBBB) and \> 20 minutes of cardiac chest pain
2. Written informed consent

Exclusion Criteria

Participant may not enter study if ANY of the following apply

1. Contraindication to MRI (implanted pacemaker/ defibrillator, ferromagnetic metal implant/ injury, claustrophobia, obesity/ too large for CMR scanner)
2. Known allergy to gadolinium
3. Chronic atrial fibrillation
4. Renal impairment with eGFR \<30
5. Cardiogenic shock
6. Patients with special communication needs
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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University of Bristol

OTHER

Sponsor Role lead

Responsible Party

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Elisa McAlindon

Cardiology Clinical Research Fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Elisa McAlindon, BMBS

Role: PRINCIPAL_INVESTIGATOR

University of Bristol

Locations

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Bristol Heart Institute

Bristol, , United Kingdom

Site Status

Countries

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United Kingdom

References

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McAlindon EJ, Pufulete M, Harris JM, Lawton CB, Moon JC, Manghat N, Hamilton MC, Weale PJ, Bucciarelli-Ducci C. Measurement of myocardium at risk with cardiovascular MR: comparison of techniques for edema imaging. Radiology. 2015 Apr;275(1):61-70. doi: 10.1148/radiol.14131980. Epub 2014 Oct 21.

Reference Type DERIVED
PMID: 25333474 (View on PubMed)

Other Identifiers

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Study 1569

Identifier Type: -

Identifier Source: org_study_id

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