Myocardial Blood Flow by 15O Water PET

NCT ID: NCT01805193

Last Updated: 2019-02-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

22 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-12-31

Study Completion Date

2019-01-31

Brief Summary

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Coronary heart disease is a very common condition caused by narrowings in the blood vessel supplying the heart. the investigators are studying new tests to diagnose heart disease. In this study the investigators plan to investigate a special scan called a PET/CT (Positron emission tomography/computed tomography) and a new type of CT (Computed tomography) scan to tell us about the flow of blood to the heart muscle.

Detailed Description

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Participants will undergo PET/CT with oxygen-15 labelled water and computed tomography myocardial perfusion imaging.

Conditions

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Coronary Heart Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Suspected coronary heart disease

Computed tomography myocardial perfusion imaging

Intervention Type OTHER

Oxygen 15 labelled water positron emission tomography

Intervention Type OTHER

Interventions

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Computed tomography myocardial perfusion imaging

Intervention Type OTHER

Oxygen 15 labelled water positron emission tomography

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* suspected coronary artery disease

Exclusion Criteria

* inability or unwillingness to undergo CT or PET imaging
* renal failure (serum creatinine \>200 um/L or eGFR \<30 ml/min)
* hepatic failure
* allergy to iodinated contrast
* pregnancy
* contraindication to adenosine
* inability to give informed consent
* atrial fibrillation with a fast ventricular rate (\>70 beats per minute)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Edinburgh

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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David Newby, PhD DM

Role: PRINCIPAL_INVESTIGATOR

University of Edinburgh

Locations

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Clinical Research Imaging Centre

Edinburgh, Scotland, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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12/SS/0078

Identifier Type: -

Identifier Source: org_study_id

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