Evaluation of Left Ventricular Function by Speckle Tracking Echocardiography in Patient Hospitalised in Intensive Care Unit for Vaso-occlusive Crisis

NCT ID: NCT04864041

Last Updated: 2021-04-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2023-12-01

Brief Summary

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Vaso-occlusive crisis in Sickle cell disease might alter myocardial function through micro vascular obstruction. Evaluation of strain alteration using speckle tracking echocardiography is a non invasive technique that may allow us to observe such myocardial dysfunction. No such study has yet been conducted in patient hospitalised in intensive care unit. Our hypothesis is that strain alteration during vaso-occlusive crisis, if they do exist, can be correlated with other markers of myocardial injury such as troponin level or thoracic pain.

Detailed Description

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Conditions

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Sickle Cell Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients hospitalised in ICU for vaso-occlusive crisis

Evaluation of global longitudinal strain using routinely recorded echocardiography images

Intervention Type OTHER

There are no particular intervention performed in patients in this study, because echocardiography is part of the standard of care of patients hospitalised in the ICU for vaso occlusive crisis.

Interventions

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Evaluation of global longitudinal strain using routinely recorded echocardiography images

There are no particular intervention performed in patients in this study, because echocardiography is part of the standard of care of patients hospitalised in the ICU for vaso occlusive crisis.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Hospitalisation in an intensive care unit for vaso-occlusive crisis

Exclusion Criteria

* Pregnancy
* Individuals under guardianship
* Unsufficient echogenicity
* Thoracic pain prohibiting echocardiography assessment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bicetre Hospital

OTHER

Sponsor Role lead

Responsible Party

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Xavier Monnet

Clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Medical Intensive Care Unit

Le Kremlin-BicĂȘtre, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Xavier Monnet, MD, PhD

Role: CONTACT

00331 45 21 35 39

Facility Contacts

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Xavier Monnet, MD, PhD

Role: primary

00331 45 21 35 39

Other Identifiers

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2021-A00623-38

Identifier Type: -

Identifier Source: org_study_id

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