The Impact of the Biologist Performing the Embryo Transfer on the Cycle Outcome

NCT ID: NCT04827771

Last Updated: 2021-04-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2000-01-01

Study Completion Date

2019-12-31

Brief Summary

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This is a retrospective single center analysis which includes all the fresh, IOC (insemination of in vitro matured oocytes) and frozen embryo transfer (ET) performed between January 2000 and December 2019 at Humanitas Fertility Center after IVF-ICSI (In Vitro Fertilization - Intracytoplasmic Sperm Injection) cycles.

The primary objective is to determine the impact of the biologist performing the embryo transfer on the pregnancy probability, in terms of ongoing pregnancy rate (OPR), defined as the number of viable pregnancies that had completed at least 12 weeks of gestation on the total number of ET performed.

Secondary end point is to evaluate whether the biologists improve their performances as their experience increases, allowing the drawing of an ET learning curve in term of pregnancies for the different biologists.

The biologist's experience was assessed in terms of number of previous interventions performed prior to the day of ET. A total of 28 operators were eligible to participate in the study. Any biologists who performed less than 100 ETs was excluded from the analysis.

Detailed Description

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Conditions

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Infertility

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Exclusion Criteria

Any biologist who performed less than 100 embryo transfers was excluded from the analysis.
Minimum Eligible Age

18 Years

Maximum Eligible Age

43 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Istituto Clinico Humanitas

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

References

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Li H, Li L, Lu X, Sun X, Ng EHY. Comparison of the effect of immediate versus delayed transfer following a stimulated IVF cycle on the ongoing pregnancy rate of frozen-thawed embryo transfer cycles: a study protocol for a randomised controlled trial. BMJ Open. 2018 May 17;8(5):e020507. doi: 10.1136/bmjopen-2017-020507.

Reference Type BACKGROUND
PMID: 29773699 (View on PubMed)

Other Identifiers

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2021-407

Identifier Type: -

Identifier Source: org_study_id

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