Effect of Oocyte Denudation Time and Intracytoplasmic Sperm Injection Time on Embryo Quality

NCT ID: NCT05448859

Last Updated: 2022-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2019-12-31

Brief Summary

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An observational analytic retrospective study was conduct using cross-sectional study. The subject were oocytes from in-vitro fertilization procedures using the ICSI method at the assisted reproductive technology clinic in a private hospital in Bandung for the period 2017 - 2019. Three variables were oocyte denudation time, ICSI time and embryo quality collected from samples that met the research criteria.

Detailed Description

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This study analyses the different oocyte denudation time after ICSI on all embryos generated during IVF procedures between 1 Januaryr 2017 and 31 December 2019. All oocytes arer categorised on how many hours their denudation times were and these were then assessed for their qualities.

Conditions

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Fertility Disorders

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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3-4 hours denudation

oocytes with 3-4 hours denudation time

intracytoplasmic sperm injection

Intervention Type PROCEDURE

injection of sperm into an oocyte in assisted reproductive technology

4-5 hours denudation

oocytes with 4-5 hours denudation time

intracytoplasmic sperm injection

Intervention Type PROCEDURE

injection of sperm into an oocyte in assisted reproductive technology

5-6 hours denudation time

oocytes with 5-6 hours denudation time

intracytoplasmic sperm injection

Intervention Type PROCEDURE

injection of sperm into an oocyte in assisted reproductive technology

6-7 hours denudation time

oocytes with 6-7 hours denudation time

intracytoplasmic sperm injection

Intervention Type PROCEDURE

injection of sperm into an oocyte in assisted reproductive technology

more than 7 hours denudation time

oocytes with more than 7 hours denudation time

intracytoplasmic sperm injection

Intervention Type PROCEDURE

injection of sperm into an oocyte in assisted reproductive technology

Interventions

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intracytoplasmic sperm injection

injection of sperm into an oocyte in assisted reproductive technology

Intervention Type PROCEDURE

Other Intervention Names

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ICSI

Eligibility Criteria

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Inclusion Criteria

* oocytes collected from in-vitro fertilisation procedures involving intracytoplasmic sperm injection

Exclusion Criteria

* oocytes from patients \>40 years old
* oocytes from primary infertility \>5 years
* endometriosis
* polycystic ovarian syndrome
Minimum Eligible Age

3 Hours

Maximum Eligible Age

8 Hours

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitas Padjadjaran

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Dian Tjahyadi

Role: PRINCIPAL_INVESTIGATOR

Universitas Padjadjaran

References

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Isiklar A, Mercan R, Balaban B, Alatas C, Aksoy S, Urman B. Impact of oocyte pre-incubation time on fertilization, embryo quality and pregnancy rate after intracytoplasmic sperm injection. Reprod Biomed Online. 2004 Jun;8(6):682-6. doi: 10.1016/s1472-6483(10)61649-5.

Reference Type RESULT
PMID: 15169586 (View on PubMed)

Other Identifiers

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OBGY-202206.02

Identifier Type: -

Identifier Source: org_study_id

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