Pregnancy Rate in Direct Versus Afterload Technique of Embryo Transfer

NCT ID: NCT05364528

Last Updated: 2022-05-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

8127 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-01

Study Completion Date

2021-12-31

Brief Summary

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The primary outcome of the study is to determine if a difference in terms of pregnancy rate exists between direct and afterload embryo transfer (ET) techniques.

The secondary end points include the evaluation of the difficult transfer rates.

Detailed Description

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The study database includes all the single fresh and frozen (G5-G6) blastocyst transfers performed at Humanitas Fertility Centre between 1st January 2016 and 31th December 2021 by using the direct and afterload protocols.

Any blastocysts that underwent preimplantation genetic testing will be excluded from the analysis, as well as embryos derived from gamete donation or those imported from other centers.

Data are gathered using a specific internal web-based database, which allows to organize, store and readily retrieve information about patients and IVF cycle.

Conditions

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Fertility Issues IVF Embryo Transfer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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clinical pregnancies with direct catheter

Clinical pregnancies occurred after fresh and frozen blastocyst transfers using direct technique.

No interventions assigned to this group

clinical pregnancies with afterload catheter

Clinical pregnancies occurred after fresh and frozen blastocyst transfers using afterload technique.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* IVF procedure
* Fresh and frozen single blastocyst transfer

Exclusion Criteria

* Any blastocysts that underwent PGS testing
* Embryos derived from gamete donation
* Embryos imported from other centers
Minimum Eligible Age

18 Years

Maximum Eligible Age

43 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Istituto Clinico Humanitas

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

References

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Cirillo F, Immediata V, Ronchetti C, Carletti T, Morenghi E, Albani E, Baggiani A, Levi-Setti PE. Steps forward in embryo transfer technique: a retrospective study comparing direct versus afterload catheters at different time frames. J Assist Reprod Genet. 2023 Dec;40(12):2895-2902. doi: 10.1007/s10815-023-02957-y. Epub 2023 Oct 11.

Reference Type DERIVED
PMID: 37819552 (View on PubMed)

Other Identifiers

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12022

Identifier Type: -

Identifier Source: org_study_id

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