Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
10 participants
INTERVENTIONAL
2015-04-02
2016-05-03
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
TRIPLE
Study Groups
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Simvastatin group
simvastatin gel (1.2 mg/0.1 ml of solid lipid nanoparticles) was locally applied to fill the jumping distance.
Simvastatin
single injection of simvastatin gel in the gap around immediately placed implant
Control group
the solid lipid nanoparticles carrier was injected into the jumping distance.
Placebo
single injection of the solid lipid nanoparticle carrier in the gap around immediately placed implant
Interventions
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Simvastatin
single injection of simvastatin gel in the gap around immediately placed implant
Placebo
single injection of the solid lipid nanoparticle carrier in the gap around immediately placed implant
Eligibility Criteria
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Inclusion Criteria
* requiring the extraction of 2 non-restorable maxillary canine or premolar on each side of the arch
* following extraction, the crestal bone had to be located 3 mm apical to the free gingival margin
* at least 3 mm of bone beyond the root apex was required to guarantee implant primary stability
Exclusion Criteria
* compromised general health conditions that would impair bone healing including present history of bone irradiation, patient on bisphosphonates therapy, antitumor chemotherapy
* pregnancy
* compromised healing conditions e.g. uncontrolled diabetes mellitus
20 Years
50 Years
ALL
Yes
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Mina Adel Rizk Botros
Assistant Researcher
Other Identifiers
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PER 15-1M
Identifier Type: -
Identifier Source: org_study_id
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