Peri-implant Soft Tissue and Bone Evaluation in Fully Computer Guided Immediate Implants

NCT ID: NCT06733870

Last Updated: 2024-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-11

Study Completion Date

2024-12-20

Brief Summary

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Prospective evaluation of perimplant soft tissue and bone response to one abutment one-time concept versus provisional abutment in fully guided single immediate implant placement.

Detailed Description

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Patient selection:

The study will be conducted on total of 16 patients recruited from the outpatient clinic of Oral Medicine, Periodontology, Oral Diagnosis and Radiology department, Faculty of Dentistry, Ain-Shams University. Sixteen consecutive healthy male/female patients with single non restorable remaining maxillary root from the right second premolar to the left second premolar will be added to the study.

Sample size analysis :

A sample size of 14 (7 in each group) will be sufficient to detect an effect size of approximately 1.75, with a power (1-β error) of 0.8 (80%) using a two-sided hypothesis test, with a significance level (α error) 0.05 for data. G power program version 3.1.9.2 was used for sample size calculation.This was increased to 8 patients in each group to make up for lost follow up cases The procedure will be explained to all patients and an informed consent will be signed before their inclusion in the study.

These patients will be divided randomly into 2 groups:

Group I: will include 8 patients who will undergo guided immediate implant placement and immediate provisionalization with preplanned PMMA provisional restoration on Ti-Base Group II: will include 8 patients who will undergo guided immediate implant placement and immediate loading by using a final CAD/CAM customized abutment and a cemented CAD/CAM fabricated PMMA provisional restoration.

Conditions

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Soft Tissue Healing

Keywords

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One abutment one time Full digital workflow Immediate implant

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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immediate load with provisional restoration

immediate load with PMMA crown on Ti base

Group Type OTHER

guided immediate implant surgery

Intervention Type PROCEDURE

fully guided immediate implant placement and loading

immediate load with one abutment one time concept

immediate ;load with customized final abutment and PMMA crown

Group Type OTHER

guided immediate implant surgery

Intervention Type PROCEDURE

fully guided immediate implant placement and loading

Interventions

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guided immediate implant surgery

fully guided immediate implant placement and loading

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Males and females aged at least 18 years.
* Patients free from any systemic disease as evidenced by health questionnaire - - Single tooth failure of a maxillary anterior region (incisors, canines, and premolars) with neighbouring teeth present and healthy periodontal conditions.
* Intact socket walls evident on cone beam computed tomography and confirmed on the day of extraction.
* Natural teeth present adjacent to the tooth being replaced in addition to a natural counterpart tooth present for esthetics criteria evaluation.
* Adequate bone apical to the tooth to be replaced with a minimum primary stability of 30 Ncm.
* Thick gingival biotype.

Exclusion Criteria

* Presence of active infection around the failing tooth or adjacent teeth.
* Presence of active periodontal disease and gingival recession in the esthetic area.
* Systemic diseases , pregnancy and smoking.
* Recent orthodontic treatment.
* Bruxism and parafunctional habits .
* Labial plate dehiscence, fenestration, or loss after tooth extraction
* Inability to achieve primary stability after implant placement
* Vulnerable groups: prisoners, mentally retarded, etc
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ain Shams University

OTHER

Sponsor Role lead

Responsible Party

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Nouran Abd El Nasser

Assistant lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mohamed Bissar, Associate professor

Role: STUDY_DIRECTOR

Faculty of dentistry- Ain Shams University

Ingy Nouh, lecturer

Role: STUDY_DIRECTOR

Faculty of dentistry- Ain Shams University

Hala Kamal, Professor

Role: STUDY_DIRECTOR

Faculty of dentistry- Ain Shams University

Locations

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faculty of Dentistry ASU

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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FDASU.REC ID 032124

Identifier Type: -

Identifier Source: org_study_id