Comparison of 2 Ventilatory Support Strategies During Coronavirus Disease 2019 (Covid-19) Pneumonia

NCT ID: NCT04799691

Last Updated: 2022-10-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

133 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-01

Study Completion Date

2022-01-15

Brief Summary

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This retrospective monocentric study compares 2 ventilatory support strategies on outcomes (length of stay, intubation, mortality) in patients admitted in Intensive Care Unit with Covid-19 related pneumonia : invasive strategy used during the first period and non-invasive strategies (Continuous Positive Airway Pressure, High Flow Nasal Canula, Prone Position) used during the second period.

Detailed Description

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Conditions

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COVID-19

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Invasive strategy group

Patients admitted in ICU with Covid-19 related pneumonia during COVID19 first period.

Invasive ventilation strategy

Intervention Type PROCEDURE

Use of an invasive ventilatory support strategy

Non-invasive strategy group

Patients admitted in ICU with Covid-19 related pneumonia during COVID19 second period.

Non-invasive ventilation strategies

Intervention Type PROCEDURE

Use of non-invasive ventilatory support strategies

Interventions

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Invasive ventilation strategy

Use of an invasive ventilatory support strategy

Intervention Type PROCEDURE

Non-invasive ventilation strategies

Use of non-invasive ventilatory support strategies

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patient with confirmed SARS COV2 infection
* Acute Respiratory Distress Syndrome
* Patient more than 18 year old

Exclusion Criteria

* Intensive Care Unit admission for extra pulmonary failure
* "Do Not Reanimated" order
* Patient from another Intensive Care Unit
* Patient objection
* Judicial protection
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Aude Garnero, MD

Role: STUDY_DIRECTOR

Centre Hospitalier Intercommunal Toulon La Seyne sur Mer

Locations

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Hôpital Sainte Musse

Toulon, Var, France

Site Status

Countries

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France

Other Identifiers

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2021-CHITS-004

Identifier Type: -

Identifier Source: org_study_id

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