4D Medical X-ray Velocimetry for Bronchoscopic Lung Volume Reduction Targeting

NCT ID: NCT04786171

Last Updated: 2024-06-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

17 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-07

Study Completion Date

2024-05-30

Brief Summary

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This study will investigate the utility of 4D Medical's X-ray Velocimetry (XV) imaging analysis software for the detection of hyperinflation, and compare endobronchial valve placement outcomes with predictive indices obtained utilizing this technique.

Detailed Description

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Conditions

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Copd Emphysema Hyperinflation

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Interventions

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4D X-ray Velocimetry

X-ray velocimetry uses fluoroscopy to quantify local ventilation in the lung.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* CT chest and PFTs within the last two years
* Age over 18
* COPD with emphysema
* Global Initiative for Chronic Obstructive Lung Disease (GOLD) 3 - 4 classification OR modified Medical Research Council (mMRC) score of 2 or greater.

Exclusion Criteria

* Pregnancy
* Presence of an additional pulmonary disease beyond COPD
* Inability to raise arms above 90 degrees as required for fluoroscopy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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American Thoracic Society

OTHER

Sponsor Role collaborator

Vanderbilt University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Michael Lester

Fellow/Assistant Professor of Pulmonary and Critical Care Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Vanderbilt University Medical Center

Nashville, Tennessee, United States

Site Status

Countries

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United States

Other Identifiers

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12345678910

Identifier Type: -

Identifier Source: org_study_id

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