DECT Ventilation Imaging

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-06-30

Study Completion Date

2016-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Demonstrate the feasibility of dual energy computed tomography using Krypton as a gaseous contrast media in order to study the in vivo ventilation.

Two different clinical situations will be tested :

* Prediction of postoperative pulmonary function for oncologic patients
* Detection of Bronchiolitis Obliterans in lung transplant recipients.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

4DX for the Diagnosis of Constrictive Bronchiolitis

NCT04489758

Constrictive Bronchiolitis

COMPLETED NA

4D Medical X-ray Velocimetry for Bronchoscopic Lung Volume Reduction Targeting

NCT04786171

Copd Emphysema Hyperinflation

COMPLETED

Early Detection of Ventilator-associated Pneumonia (VAP)

NCT02753608

Pneumonia, Ventilator-associated

COMPLETED NA

Quantitative Computed Tomography for Mortality Risk Stratification in ARDS

NCT06113276

Acute Respiratory Distress Syndrome

RECRUITING

Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant

NCT03667027

Diaphragm Injury Respiratory Failure Mechanical Ventilation Complication

RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

For Oncologic Patients Potentially Operable Lung Tumor With a Recent (Less Than 1 Month) VQ Scan For Lung Transplant Recipients Single of Bilateral Lung Transplant From 5 Months Onwards With Recent (Less Than 1 Month) Respiratory Functional Explorations

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

oncologic patients

Prediction of postoperative pulmonary function.

Patients with an operable lung cancer: dual energy computed tomography with Krypton will be tested to estimate the postoperative FEV1

Group Type EXPERIMENTAL

Single source dual energy compted tomography (CT750HD, General Electric, USA) with Krypton as a gaseous contrast media

Intervention Type RADIATION

lung transplant recipients

Detection of BOS

6 months+ lung transplant recipients will be tested using dual energy computed tomography with Krypton, with acquisition in the end-inspiratory and end-expiratory phase, in search of regional air trapping.

Group Type EXPERIMENTAL

Single source dual energy compted tomography (CT750HD, General Electric, USA) with Krypton as a gaseous contrast media

Intervention Type RADIATION

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Single source dual energy compted tomography (CT750HD, General Electric, USA) with Krypton as a gaseous contrast media

Intervention Type RADIATION

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

For oncologic patients :

* Potentially operable lung tumor
* With a recent (less than 1 month) V/Q scan

For lung transplant recipients :

* Single of bilateral lung transplant
* From 5 months onwards
* With recent (less than 1 month) respiratory functional explorations

Exclusion Criteria

* Impossibility to follow simple orders or control one's respiration
* Known Krypton hypersensitivity
* History of malignant hyperthermia
* Increased intracranial pressure
* Minors
* Pregnant Women

Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No