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Application of Indicator Based-electrical Impedance Tomography Method Assess Lung Regional Perfusion in ICU Patients

NCT ID: NCT04081142

Last Updated: 2020-12-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

119 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-05-01

Study Completion Date

2020-07-31

Brief Summary

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This study is an observational study. Investigate the relationship of oxgenation and lung regional ventilation and perfusion assessed by the indicator based-EIT method in the critically ill patients in ICU

Detailed Description

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1. Written informed consent was obtained from all patients or next of kin before data were included in the study.
2. When the research team was available, adult patients within 1w, who were sequentially admitted to the Department of Critical Care Medicine and required central venous catheters for resuscitation were eligible for the study.
3. Information collected at enrollment included demographic characteristics such as age, sex, Acute Physiology and Chronic Health Evaluation II score (APCHEII); . The global hemodynamic, respiration condition and PaO2 were measured. At the same time, the lung regional ventilation and perfusion assessed by the indicator based-EIT method(injection 10%NaCL).
4. The 10%NaCL was injected by the central venous catheter.

Conditions

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Respiratory Failure Hypoxemia ARDS, Human

Keywords

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EIT, pulmonary perfusion

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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acute respiratory failure group

acute respiratory failure (ARF) group: arterial oxygen partial pressure to fractional inspired oxygen ratio, PaO2/FiO2\<300 mmHg and/or peripheral oxygen saturation SaO2\<94% under air condition and/or severe dyspnea with respiratory rate \>30bpm.

No interventions assigned to this group

control group

postoperative ICU patients without ARF were included

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Time of admission ICU \< 7days
* Age (\> 18 years old)
* Have been placed central venous catheter based on clinical requirement

Exclusion Criteria

.Chest skin injured and cannot be monitored by EIT.

* Severe Hypernatremia
* Pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yun Long

OTHER

Sponsor Role lead

Responsible Party

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Yun Long

the director of the intensive care medicine

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Yun Long

Role: STUDY_CHAIR

Peking Union Medical College Hospital

Locations

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Peking Union Medical College Hospital, Chinese Academy of Medical Science

Beijing, Beijing Municipality, China

Site Status

Countries

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China

References

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Wang Q, Su L, Jiang J, Wang N, He H, Long Y. Incorporating electrical impedance tomography to transpulmonary pressure-guided PEEP in severe ARDS with pneumothorax and multiple cavitations: a case report. Front Med (Lausanne). 2023 Aug 28;10:1240321. doi: 10.3389/fmed.2023.1240321. eCollection 2023.

Reference Type DERIVED
PMID: 37700773 (View on PubMed)

He H, Chi Y, Long Y, Yuan S, Zhang R, Yang Y, Frerichs I, Moller K, Fu F, Zhao Z. Three broad classifications of acute respiratory failure etiologies based on regional ventilation and perfusion by electrical impedance tomography: a hypothesis-generating study. Ann Intensive Care. 2021 Aug 28;11(1):134. doi: 10.1186/s13613-021-00921-6.

Reference Type DERIVED
PMID: 34453622 (View on PubMed)

Other Identifiers

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EIT-lung Perfusion in ICU

Identifier Type: -

Identifier Source: org_study_id