Effect of PEEP on Lung Regional Ventilation and Perfusion

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

33 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-01

Study Completion Date

2020-06-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Investigate effects of PEEP on pulmonary regional ventilation and perfusion assessed by EIT

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Application of Indicator Based-electrical Impedance Tomography Method Assess Lung Regional Perfusion in ICU Patients

NCT04081142

Respiratory Failure Hypoxemia ARDS, Human

COMPLETED

Association Between EIT and CT During PEEP Titration in Patients With Acute Respiratory Failure

NCT07175194

Acute Hypoxemic Respiratory Failure Ventilation, Mechanical

NOT_YET_RECRUITING

The Study of Regional Lung Ventilation-perfusion by EIT

NCT05105932

Pulmonary Ventilation Pulmonary Perfusion

UNKNOWN

Assessing Lung Inhomogeneity During Ventilation for Acute Hypoxemic Respiratory Failure

NCT03589482

Acute Respiratory Distress Syndrome Mechanical Ventilation Pressure High Hypoxemic Respiratory Failure

COMPLETED NA

Effect of Electric Impedance Tomography-Guided PEEP Titration

NCT05736185

ARDS, Human

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

1. When the research team was available, adult patients within 7days who were sequentially admitted to the Department of Critical Care Medicine and required central venous catheters and mechanically ventilation were eligible for the study.
2. Written informed consent was obtained from all patients or next of kin before data were included in the study.
3. Information collected at enrollment included demographic characteristics, such as age, sex.
4. The blood pressure（BP）,heart rate（HR）, pulse O2（SpO2）,tidal volume and lung regional ventilation and perfusion were collected at PEEP 0 centimeter H2O column and PEEP 12-15 centimeter H2O column.
5. Indicator-based EIT method: rapidly inject 10ml 10% Sodium chloride（NaCL） through central venous catheter during a 8s respiratory hold, and the curve of impedence change was collected by EIT machine

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Mechanical Ventilation Complication Respiratory Failure Hypoxia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. have been placed central venous catheter based on patient's condition
2. Under mechanically ventilation
3. Under sedation and control ventilation mode
4. Year\>18