The Bern Perioperative Biobank

NCT ID: NCT04767685

Last Updated: 2022-11-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

547 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-01-31

Study Completion Date

2021-12-31

Brief Summary

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The goal of the research is to define clinically relevant molecular markers for increased risk of peri-/ postoperative organo-dysfunctions, inflammation, adverse events and disease progression. To better understand the perioperative impact the investigators aim to determine perioperative levels of molecular markers over time in the available samples and clinical data of the Bern perioperative Biobank (BPBB) cohort to finally increase quality of perioperative care of patients by permitting preventive measures to be taken early in patients at risk.

Detailed Description

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Conditions

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Anesthesia Surgical Procedure, Operative

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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All patients

Consenting patients undergoing non-emergency surgery with anesthesia

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* 18 years and older
* Written informed consent
* Non-emergency surgery

Exclusion Criteria

* Transient incapacity to consent or insufficient time (\< 6h) to consider study participation
* No informed consent
* Cognitive impairment/Patients unable to consent
* Patients who retrospectively expressed their wish to be excluded
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Insel Gruppe AG, University Hospital Bern

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Frank Stüber, Prof. MD

Role: STUDY_CHAIR

Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern

Markus M Lüdi, MD

Role: STUDY_DIRECTOR

Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern

Locations

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Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern

Bern, , Switzerland

Site Status

Countries

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Switzerland

References

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Bello C, Filipovic MG, Huber M, Flannery S, Kobel B, Fischer R, Kessler BM, Raber L, Stueber F, Luedi MM. Discovery of plasma proteome markers associated with clinical outcome and immunological stress after cardiac surgery. Front Cardiovasc Med. 2023 Dec 22;10:1287724. doi: 10.3389/fcvm.2023.1287724. eCollection 2023.

Reference Type DERIVED
PMID: 38379859 (View on PubMed)

Heinisch PP, Mihalj M, Huber M, Schefold JC, Hartmann A, Walter M, Steinhagen-Thiessen E, Schmidli J, Stuber F, Raber L, Luedi MM. Impact of Lipoprotein(a) Levels on Perioperative Outcomes in Cardiac Surgery. Cells. 2021 Oct 21;10(11):2829. doi: 10.3390/cells10112829.

Reference Type DERIVED
PMID: 34831051 (View on PubMed)

Other Identifiers

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041/09f

Identifier Type: -

Identifier Source: org_study_id

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