The Effect of Two Different Artificial Respiration Methods on the Intraocular Pressure During Surgery Under General Anesthesia

NCT ID: NCT01567761

Last Updated: 2012-03-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-05-31

Brief Summary

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The purpose of this study is to examine whether the intraocular pressure of operated people under general anesthesia is affected by the artificial respiration method. If it is proven that there is such influence, the findings may lead to select the best method for patients with increased intraocular pressure.

In this study, the investigators will monitor the changes observed in intraocular pressure caused during an operation in two different artificial respiration methods:

1. Intermittent positive pressure ventilation (IPPV)
2. High frequency jet ventilation (HFJV)

Study recruited 50 patients aged 18 - 40, candidates to elective orthopedic surgery in the limbs. These patients do not suffer from general diseases that restrict their daily functioning.

The selection of the type of surgery was done to prevent the involvement of any other factor, except the respiration method, determination of intraocular pressure.

Exclusion Criteria:

* Patients who are unable to provide an Informed Consent
* Patients suffering from any eye disease
* Patients with corneal thickness less than 450 microns or more than 600 microns
* Smokers
* Patients with pulmonary disease restrictive or obstructive
* Patients using bronchodilator

All patients operated under general anesthesia using total intravenous anesthesia )TIVA) method.

All patients will be resuscitating half of the time of surgery using IPPV, and in the second half of surgery using HFJV.

During the surgery the IOP will be measured by an ophthalmologist who is unaware of the respiration method.

Correction will be made to the intraocular pressure values, depending on the thickness of the cornea.

The results of the measurements will be collected and the clinical significance will be reviewed by acceptable statistical methods.

Detailed Description

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Conditions

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Intra Ocular Hypertension

Keywords

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IOP

Study Design

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Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 - 40
* Patients candidates to elective orthopedic surgery in the limbs
* Patients do not suffer from general diseases that restrict their daily functioning.

Exclusion Criteria

* Patients who are unable to provide an Informed Consent
* Patients suffering from any eye disease
* Patients with corneal thickness less than 450 microns or more than 600 microns
* Smokers
* Patients with pulmonary disease restrictive or obstructive
* Patients using bronchodilator
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Western Galilee Hospital-Nahariya

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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Zvi Segal, M.D.

Role: CONTACT

Phone: 972-50-7887602

Email: [email protected]

Other Identifiers

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3111

Identifier Type: -

Identifier Source: org_study_id