Continuous and Discontinuous Determination of Propofol Concentration in Breathing Gas

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

16 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-09-30

Study Completion Date

2010-12-31

Brief Summary

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This study should compare the propofol concentration in breathing gas and in plasma (before and) after lung passage. Propofol concentrations in breathing gas are continuously measured by a sensor. For comparison a discontinuous method is used. Neurophysiologic parameters for determination of depth of anesthesia are compared to the continuous measured propofol concentration in breathing gas.

Study hypothesis: continuous measured propofol concentration in breathing gas correlates to propofol concentration in plasma and depth of anaesthesia.

Detailed Description

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Conditions

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General Anesthesia

Keywords

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Monitoring Breathing Gas Propofol

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patient destined for general anesthesia

Exclusion Criteria

* Heart insufficiency NYHA IV
* Allergy to propofol

Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Martin Grossherr

Consultant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hartmut Gehring, MD, PhD

Role: STUDY_DIRECTOR

Dept of Anesthesiology, UK-SH, Campus Luebeck

Locations

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Dept. of Anesthesiology , UK-SH, Campus Luebeck

Lübeck, Schleswig-Holstein, Germany

Site Status

Dept. of Anesthesiology, UK-SH, Campus Luebeck

Lübeck, Schleswig-Holstein, Germany

Site Status

Countries

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Germany

References

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Grossherr M, Hengstenberg A, Meier T, Dibbelt L, Gerlach K, Gehring H. Discontinuous monitoring of propofol concentrations in expired alveolar gas and in arterial and venous plasma during artificial ventilation. Anesthesiology. 2006 Apr;104(4):786-90. doi: 10.1097/00000542-200604000-00024.

Reference Type RESULT

PMID: 16571975 (View on PubMed)

Other Identifiers

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P-A-S-1

Identifier Type: -

Identifier Source: org_study_id