Primary vs Secondary Closure of Tracheo-cutaneous Fistulas

NCT ID: NCT04647968

Last Updated: 2024-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-12

Study Completion Date

2026-07-31

Brief Summary

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The mean of this study is to compare primary and secondary closure of tracheo-cutaneous fistulas and evaluate the differences in outcomes between both techniques.

Detailed Description

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In this study the investigators wish to recruit patients with a tracheotomy that has been installed for various reasons and that is ready for closure. The investigators intend to randomly allocate them a mean of closure, either primary or secondary. Once the fistula is closed, the investigators will follow them over a substantial period of time to compare outcomes of each mean of closing. Different questionnaires will be used to best evaluate a range of variables.

Conditions

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Tracheostomy Complication Post Tracheostomy Complications Tracheostomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized Controlled Trial
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

No masking because it is a surgical procedure

Study Groups

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Primary closure of tracheo-cutaneous fistula

This group will undergo a protocoled primary closure of their tracheotomy.

Group Type OTHER

Primary closure of tracheo-cutaneous fistula

Intervention Type PROCEDURE

This procedure will follow protocoled steps. It consists of a sutured closure of the tracheotomy following local anesthesia, done at bedside.

Secondary closure of tracheo-cutaneous fistula

This group will undergo a protocoled secondary closure of their tracheotomy.

Group Type OTHER

Secondary closure of tracheo-cutaneous fistula

Intervention Type PROCEDURE

This procedure will follow protocoled steps. It consists of removing the tracheotomy canula and applying ointment and an Elastoplast on the site, which will be changed regularly until full healing of the wound.

Interventions

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Primary closure of tracheo-cutaneous fistula

This procedure will follow protocoled steps. It consists of a sutured closure of the tracheotomy following local anesthesia, done at bedside.

Intervention Type PROCEDURE

Secondary closure of tracheo-cutaneous fistula

This procedure will follow protocoled steps. It consists of removing the tracheotomy canula and applying ointment and an Elastoplast on the site, which will be changed regularly until full healing of the wound.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Being covered by the RAMQ
* Having a tracheostomy either percutaneous or surgical
* Being ready for canula removal and closure of the fistula

Exclusion Criteria

* Presenting a contraindication to primary tracheotomy closure (granuloma)
* Unable to consent
* Refusal to participate
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Université de Sherbrooke

OTHER

Sponsor Role lead

Responsible Party

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Simon Brisebois

Assistant Professor - Division of Otolaryngology - Head & Neck Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Simon Brisebois, MD, MSC

Role: PRINCIPAL_INVESTIGATOR

Université de Sherbrooke

Locations

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Centre hospitalier universitaire de Sherbrooke

Sherbrooke, Quebec, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Simon Brisebois, MD, MSC

Role: CONTACT

8193461110 ext. 24947

Brigitte Routhier-Chevrier, MD

Role: CONTACT

8193461110 ext. 24947

Facility Contacts

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Simon Brisebois, MD MSc

Role: primary

819-346-1110 ext. 14901

Adnan Busuladzic, MD

Role: backup

819-346-1110 ext. 14901

Other Identifiers

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2021-3699

Identifier Type: -

Identifier Source: org_study_id

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