Fistulectomy vs. Modified Karydakis Procedure for Pilonidal Sinus

NCT ID: NCT03271996

Last Updated: 2017-09-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-04-30

Study Completion Date

2017-06-30

Brief Summary

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This study wants to improve patient care affected by pilonidal sinus during and after surgery. Pilonidal sinus excision is a frequent procedure, despite this, there is still not an appropriate surgical technique because of a lack of quality comparative studies.

Detailed Description

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This is a randomized controlled trial. The study will compare the healing of the surgical wound and the recurrence rate after excision and primary para-median closure versus narrow orifice excision (fistulectomy)

Group A: excision and paramedian closure according to modified Karydakis technique

Group B: removal / fistulectomy by scalpels or trephines of primary and drainage orifices, healing of the wound by secondary intention

Conditions

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Pilonidal Sinus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized controlled study
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Primary closure

Excision of sinus and paramedian closure according to modified Karydakis technique

Group Type EXPERIMENTAL

Primary closure

Intervention Type PROCEDURE

Asymmetric skin incision and total excision of the lesion with monopolar scalpel. Accurate hemostasis, creation of a cutaneous-subcutaneous flap, primary closure with non-absorbable sutures, optional aspiration drainage.

Fistulectomy

Removal / fistulectomy by scalpels or trephines of primary and drainage orifices and healing of the wound by second intention

Group Type EXPERIMENTAL

Fistulectomy

Intervention Type PROCEDURE

Evaluation of the cavity using a 0.5-1 mm metal probe which will be inserted into the skin orifice. Excision of the skin around the orifice and debridement/excision of the cavity by monopolar scalpel or Trephines

Interventions

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Primary closure

Asymmetric skin incision and total excision of the lesion with monopolar scalpel. Accurate hemostasis, creation of a cutaneous-subcutaneous flap, primary closure with non-absorbable sutures, optional aspiration drainage.

Intervention Type PROCEDURE

Fistulectomy

Evaluation of the cavity using a 0.5-1 mm metal probe which will be inserted into the skin orifice. Excision of the skin around the orifice and debridement/excision of the cavity by monopolar scalpel or Trephines

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Pilonidal cyst requiring surgery
* Signed Informed Consent Form

Exclusion Criteria

* Abnormal lesions
* Injuries requiring a closing with rotation flap
Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dimitri Christoforidis

OTHER

Sponsor Role lead

Responsible Party

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Dimitri Christoforidis

Vice-Chief in Surgery

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Ospedale Regionale di Lugano

Lugnao, , Switzerland

Site Status

Countries

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Switzerland

References

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Popeskou SG, Pravini B, Panteleimonitis S, Vajana AFDT, Vanoni A, Schmalzbauer M, Posabella A, Christoforidis D. Conservative Sinusectomy vs. excision and primary off-midline closure for pilonidal disease: a randomized controlled trial. Int J Colorectal Dis. 2020 Jul;35(7):1193-1199. doi: 10.1007/s00384-020-03551-9. Epub 2020 Mar 6.

Reference Type DERIVED
PMID: 32144531 (View on PubMed)

Other Identifiers

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11-016

Identifier Type: -

Identifier Source: org_study_id

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