Evaluation of Additional Heidelberg Engineering SPECTRALIS With OCT Angiography Module (OCTA Module) Scan Types

NCT ID: NCT04604002

Last Updated: 2024-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

86 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-10-15

Study Completion Date

2022-01-04

Brief Summary

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Assessment of image quality and clinical relevance of OCT Angiography at different speed/ART combinations

Detailed Description

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The objectives of this study are:

1.) Compare the image quality between the predicate scan types and the corresponding investigational scan types.

2\. Compare the visibility of key anatomical vascular structures between the predicate scan types and the corresponding investigational scan types.

3\. Assess the agreement in identification of vascular abnormalities between the predicate scan types and the corresponding investigational scan types, where agreement is assessed by the vascular abnormalities identified from the predicate scan types.

Conditions

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Retinal Vascular Normal Eyes

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Subjects with Normal Eyes

OCT, Color Fundus Photography and OCT Angiography as per protocol in subjects without ophthalmic pathology

OCT Angiography

Intervention Type DEVICE

OCT Angiography offers clinicians a non-invasive three-dimensional visualization of vasculature in the retina and choroid. The visualization of perfused vasculature in a three-dimensional layout, offers clinicians an aid in the identification of retinal and choroidal pathologies such as retinal ischemia, microaneurysms, retinal neovascularization and choroidal neovascular membranes.

Color Fundus Photography

Intervention Type DEVICE

Non-contact white light photography

Optical Coherence Tomography

Intervention Type DEVICE

A non-contact test that uses light waves to take cross-sectional pictures of the retina

Subjects with Pathology

OCT, Color Fundus Photography and OCT Angiography as per protocol in subjects with retinal vascular pathology

OCT Angiography

Intervention Type DEVICE

OCT Angiography offers clinicians a non-invasive three-dimensional visualization of vasculature in the retina and choroid. The visualization of perfused vasculature in a three-dimensional layout, offers clinicians an aid in the identification of retinal and choroidal pathologies such as retinal ischemia, microaneurysms, retinal neovascularization and choroidal neovascular membranes.

Color Fundus Photography

Intervention Type DEVICE

Non-contact white light photography

Optical Coherence Tomography

Intervention Type DEVICE

A non-contact test that uses light waves to take cross-sectional pictures of the retina

Interventions

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OCT Angiography

OCT Angiography offers clinicians a non-invasive three-dimensional visualization of vasculature in the retina and choroid. The visualization of perfused vasculature in a three-dimensional layout, offers clinicians an aid in the identification of retinal and choroidal pathologies such as retinal ischemia, microaneurysms, retinal neovascularization and choroidal neovascular membranes.

Intervention Type DEVICE

Color Fundus Photography

Non-contact white light photography

Intervention Type DEVICE

Optical Coherence Tomography

A non-contact test that uses light waves to take cross-sectional pictures of the retina

Intervention Type DEVICE

Other Intervention Names

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Optical Coherence Tomography Angiography OCTA CFP OCT

Eligibility Criteria

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Inclusion Criteria

* All Populations:

1. Able and willing to undergo the test procedures, sign informed consent, and follow instructions.
2. Age ≥ 22
* Normal Population:

3\. Subjects without uncontrolled systemic conditions, as determined by the Investigator 4. Subjects without ocular disease, as determined by the Investigator 5. Corrected visual acuity ≥ 20/40 6. No reported history of ocular surgical intervention (except for refractive or cataract surgery)
* Pathology Population:

3\. Subjects with vascular abnormalities such as retinal ischemia, microaneurysms, choroidal neovascularization, retinal neovascularization in at least one eye

Exclusion Criteria

* All Populations:

1. Subjects unable to read or write
2. Subjects with ocular media not sufficiently clear to obtain acceptable study-related imaging
3. Subjects who cannot tolerate the imaging procedures
4. Subjects without an accompanying structural OCT and CFP image for an acceptable OCTA image
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Heidelberg Engineering GmbH

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Dennis Marcus, MD

Role: PRINCIPAL_INVESTIGATOR

Southeast Retina Center

Locations

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Southeast Retina Center

Augusta, Georgia, United States

Site Status

Countries

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United States

Other Identifiers

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S-2020-5

Identifier Type: -

Identifier Source: org_study_id

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