Evaluation of the Heidelberg Engineering SPECTRALIS With Flex Module for In-vivo Imaging in the Supine Position

NCT ID: NCT04661124

Last Updated: 2025-09-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

88 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-12-10

Study Completion Date

2024-04-22

Brief Summary

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This is a prospective clinical study conducted at one clinical site in the United States.

Detailed Description

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The conducted study is an observational study for an imaging device used in the aid of ophthalmology diagnosis.

Conditions

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Retinal Disease Healthy Eyes

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

PROSPECTIVE

Study Groups

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Adult Normal Eyes

see Inclusion/Exclusion criteria; imaged with OCT and/or OCTA

SPECTRALIS

Intervention Type DEVICE

ophthalmic imaging device with head and chinrest

SPECTRALIS with Flex Module

Intervention Type DEVICE

ophthalmic imaging device on mobile instrumentation stand

Adult Pathology Eyes

see Inclusion/Exclusion criteria; imaged with OCT and/or OCTA

SPECTRALIS

Intervention Type DEVICE

ophthalmic imaging device with head and chinrest

SPECTRALIS with Flex Module

Intervention Type DEVICE

ophthalmic imaging device on mobile instrumentation stand

Interventions

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SPECTRALIS

ophthalmic imaging device with head and chinrest

Intervention Type DEVICE

SPECTRALIS with Flex Module

ophthalmic imaging device on mobile instrumentation stand

Intervention Type DEVICE

Other Intervention Names

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SPECTRALIS HRA+OCT (and variants) with OCT Angiography Module SPECTRALIS HRA+OCT (and variants) with Flex Module

Eligibility Criteria

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Inclusion Criteria

1. Age ≥ 22 years
2. Able and willing to undergo the test procedures, sign informed consent, and follow instructions.
3. Physically able to be positioned in all required imaging positions (upright at chinrest and supine).
4. Able to fixate.
5. Best corrected visual acuity ≥ 20/40 in both eyes.


1. Age ≥ 22 years
2. Able and willing to undergo the test procedures, sign informed consent, and follow instructions.
3. Physically able to be positioned in all required imaging positions (upright at chinrest and supine).
4. Able to fixate.
5. Eye with a structural and vascular posterior segment abnormality due to ocular disease and/or trauma.

Exclusion Criteria

1. Eye with ocular media not sufficiently clear to obtain acceptable study-related imaging.
2. Subjects who cannot tolerate the imaging procedures.
3. Clinically significant ocular disease in either eye as determined by an Investigator.
4. Ocular surgical intervention (except for refractive laser surgery or cataract surgery) in either eye.

Adult Posterior Segment Abnormality Eye Population (AD)


1. Eye with ocular media not sufficiently clear to obtain acceptable study-related imaging.
2. Subjects who cannot tolerate the imaging procedures.
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Duke University

OTHER

Sponsor Role collaborator

Heidelberg Engineering GmbH

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Lejla Vajzovic, MD

Role: PRINCIPAL_INVESTIGATOR

Duke University

Locations

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Duke Eye Center

Durham, North Carolina, United States

Site Status

Countries

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United States

Other Identifiers

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S-2018-3

Identifier Type: -

Identifier Source: org_study_id

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