Evaluation of Retinal Structure With High Resolution Optical Coherence Tomography (OCT)

NCT ID: NCT00564291

Last Updated: 2023-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

700 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-01-31

Study Completion Date

2023-11-28

Brief Summary

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Comparison of different OCT instruments to assess retinal thickness, correlation to fluorescein angiography, and visual outcome after therapy with anti-VEGF therapy

Detailed Description

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Comparison of different OCT instruments to assess retinal thickness, correlation to fluorescein angiography, and visual outcome after therapy with anti-VEGF therapy

Conditions

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Macular Edema CNV

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Healthy volunteers

Examination with an OCT device

Intervention Type OTHER

2

CSME secondary to diabetic retinopathy

No interventions assigned to this group

3

ARMD with CNV before and after therapy

Examination with an OCT device

Intervention Type OTHER

4

ARMD atrophic

Examination with an OCT device

Intervention Type OTHER

5

Retinal vein occlusion

Examination with an OCT device

Intervention Type OTHER

6

retinitis pigmentosa

Examination with an OCT device

Intervention Type OTHER

7

vitreoretinal proliferation

Examination with an OCT device

Intervention Type OTHER

Interventions

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Examination with an OCT device

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Macular disease
* Healthy subjects
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Bern

OTHER

Sponsor Role collaborator

Sebastian Wolf

OTHER

Sponsor Role lead

Responsible Party

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Sebastian Wolf

Director

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Sebastian Wolf, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Bern

Sebastian Wolf, MD PhD

Role: STUDY_DIRECTOR

University of Bern

Locations

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Dep. Ophthalmology, University Hospital Bern

Bern, , Switzerland

Site Status

Klinik und Poliklinik für Augenheilkunde, University Bern

Bern, , Switzerland

Site Status

Countries

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Switzerland

References

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Lincke JB, Keller S, Amaral J, Zinkernagel MS, Schuerch K. Ciliary body length revisited by anterior segment optical coherence tomography: implications for safe access to the pars plana for intravitreal injections. Graefes Arch Clin Exp Ophthalmol. 2021 Jun;259(6):1435-1441. doi: 10.1007/s00417-020-04967-3. Epub 2020 Oct 19.

Reference Type DERIVED
PMID: 33074373 (View on PubMed)

Wolf-Schnurrbusch UE, Ghanem R, Rothenbuehler SP, Enzmann V, Framme C, Wolf S. Predictors of short-term visual outcome after anti-VEGF therapy of macular edema due to central retinal vein occlusion. Invest Ophthalmol Vis Sci. 2011 May 18;52(6):3334-7. doi: 10.1167/iovs.10-6097.

Reference Type DERIVED
PMID: 21087958 (View on PubMed)

Rothenbuehler SP, Waeber D, Brinkmann CK, Wolf S, Wolf-Schnurrbusch UE. Effects of ranibizumab in patients with subfoveal choroidal neovascularization attributable to age-related macular degeneration. Am J Ophthalmol. 2009 May;147(5):831-7. doi: 10.1016/j.ajo.2008.12.005. Epub 2009 Feb 13.

Reference Type DERIVED
PMID: 19217019 (View on PubMed)

Other Identifiers

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KEK 044/07

Identifier Type: -

Identifier Source: org_study_id