ST-Segment Resolution as a Marker for Myocardial Scar in ST-Segment Elevation Myocardial Infarction
NCT ID: NCT04586582
Last Updated: 2020-10-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
42 participants
OBSERVATIONAL
2017-07-01
2019-04-30
Brief Summary
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The investigators aimed to establish whether poor ST-segment resolution in ECG, as well as CMR-LGE, could detect the presence of myocardial scar in early STEMI patients. In order to provide convenient, cheap and widely used test method for patients who cannot tolerate CMR-LGE.
42 STEMI patients with single-branch coronary artery stenosis or occlusion were enrolled. ST-segment elevations were measured on the baseline and 24 hours after PCI. The study population was divided into two groups by late gadolinium enhanced cardiac magnetic resonance (LGE- CMR), with transmural myocardial scar (\>75%) or non-transmural myocardial scar (\<75%).
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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ST-segment resolution <40.15%
ST-segment resolution \<40.15%
ST-segment resolution <40.15%
Forty-two STEMI patients with single-branch coronary artery stenosis or occlusion were enrolled. ST-segment elevations were measured at emergency admission and at 24 h after PCI. Late gadolinium-enhanced cardiac magnetic resonance imaging (CMR-LGE) was performed 7 days after PCI to evaluate myocardial scars.
ST-segment resolution >40.15%
ST-segment resolution \>40.15%
ST-segment resolution <40.15%
Forty-two STEMI patients with single-branch coronary artery stenosis or occlusion were enrolled. ST-segment elevations were measured at emergency admission and at 24 h after PCI. Late gadolinium-enhanced cardiac magnetic resonance imaging (CMR-LGE) was performed 7 days after PCI to evaluate myocardial scars.
Interventions
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ST-segment resolution <40.15%
Forty-two STEMI patients with single-branch coronary artery stenosis or occlusion were enrolled. ST-segment elevations were measured at emergency admission and at 24 h after PCI. Late gadolinium-enhanced cardiac magnetic resonance imaging (CMR-LGE) was performed 7 days after PCI to evaluate myocardial scars.
Eligibility Criteria
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Inclusion Criteria
2. Restoration of coronary perfusion to TIMI flow grade 3 after PCI
Exclusion Criteria
2. Coronary revascularization
3. Severe chronic kidney disease
4. Intracardiac pacing leads or other implants precluding CMR-LGE
5. Hemodynamic instability
6. Known claustrophobia
30 Years
80 Years
ALL
No
Sponsors
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Chongqing Medical University
OTHER
Responsible Party
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Dongying Zhang
Clinical Professor
Principal Investigators
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Dongying Zhang, phD.
Role: STUDY_DIRECTOR
First Affiliated Hospital of Chongqing Medical University
Locations
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The first affiliated hospital of Chongqing medical university
Chongqing, Chongqing Municipality, China
Countries
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Other Identifiers
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20180701
Identifier Type: -
Identifier Source: org_study_id
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