Stress Cardiac MRI in Ischemic Patients

NCT ID: NCT04588675

Last Updated: 2020-10-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-30

Study Completion Date

2022-06-30

Brief Summary

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The aim of this study is to assess the diagnostic accuracy of CMR feature-tracking (FT) at rest \& during stress with low dose dobutamine (LDD) in the evaluation of viability in ischemic cardiomyopathy (ICM) patients and compare it with delayed gadolinium enhancement (DGE).

Detailed Description

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Conditions

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Ischemic Cardiomyopathy

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Interventions

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MRI

the patients will underwent dobutamine stress cardiac MRI

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* All patients recruited into the study have chronic LV systolic dysfunction due to coronary artery disease (CAD)

Exclusion Criteria

* All patients with a contraindication to MR study:

* Patients with implanted non-MRI compatible electronic devices (e.g. Cardiac pacemakers, intracranial metallic clips, implanted hearing aids, etc.)
* Patients with foreign bodies in the eye.
* Claustrophobic patients.
* Patients diagnosed with recent acute coronary syndrome within 4 weeks.
* Patients who had contraindications for MRI or contrast agents, and those with poor image quality due to either inadequate breath holding or arrhythmias
Minimum Eligible Age

20 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Abdulrahman Emam Eldeen

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Abdulrahman Hamdan

Role: CONTACT

1005363950 ext. 0020

References

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Bhutani M, Vatsa D, Rahatekar P, Verma D, Nath RK, Pandit N. Role of strain imaging for assessment of myocardial viability in symptomatic myocardial infarction with single vessel disease: An observational study. Echocardiography. 2020 Jan;37(1):55-61. doi: 10.1111/echo.14567. Epub 2019 Dec 23.

Reference Type BACKGROUND
PMID: 31868950 (View on PubMed)

Schuster A, Paul M, Bettencourt N, Morton G, Chiribiri A, Ishida M, Hussain S, Jogiya R, Kutty S, Bigalke B, Perera D, Nagel E. Cardiovascular magnetic resonance myocardial feature tracking for quantitative viability assessment in ischemic cardiomyopathy. Int J Cardiol. 2013 Jun 20;166(2):413-20. doi: 10.1016/j.ijcard.2011.10.137. Epub 2011 Nov 29.

Reference Type BACKGROUND
PMID: 22130224 (View on PubMed)

Other Identifiers

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Stress cardiac MRI

Identifier Type: -

Identifier Source: org_study_id

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