CMR Features in Patients With Suspected Myocarditis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

670 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-06-01

Study Completion Date

2018-02-01

Brief Summary

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Presentation of myocarditis is heterogeneous, often ranges from being asymptomatic, to chest pain, dyspnoea, palpitations, and even sudden cardiac death. Diagnosing myocarditis is challenging with no current uniform clinical gold-standard. CMR is a key investigative tool, however the predictive value of CMR features is unknown. In this study we assess 670 consecutive patients with suspected myocarditis who were referred for CMR between 2002 and 2015 at the BWH. CMR features such as late gadolinium sizing, T1 mapping, extracellular volume fraction assessment, strain analysis (feature tracking), clinical data, labortory tetsings and electrocardiogramm are linked to the outcome in order to assess its predictive value.

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Detailed Description

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Conditions

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Outcome, Fatal

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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CMR

Outcome analysis of CMR features in suspected myocarditis patients

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* patients referred by their treating physician to undergo CMR for "suspected myocarditis" as the primary clinical question

Exclusion Criteria

* evidence of coronary artery disease
* hypertrophic cardiomyopathy
* arrhythmogenic right ventricular cardiomyopathy
* cardiac sarcoidosis
* cardiac amyloidosis
* takotsubo cardiomyopathy
* constrictive pericarditis
* Loeffler endocarditis
* ventricular non-compaction
* cardiac tumor
* pulmonary embolism
* severe valve disease

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No