CMR in Myocardial Infarction with Nonobstructive Coronary Arteries

NCT ID: NCT06502899

Last Updated: 2024-07-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

387 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-01

Study Completion Date

2024-07-09

Brief Summary

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MINOCA is accompanied by a worse prognosis, which is related to the inability to clarify the etiology.CMR has been explicitly recommended by guidelines as an etiologic diagnostic tool for MINOCA. Although CMR-related parameters, such as strain and ECV, have been shown to be associated with prognosis in patients with myocardial infarction. However, the relationship between CMR-strain or ECV and MINOCA is unclear. The aim of this study was to investigate the characterization of CMR-strain or ECV in patients with MINOCA and the relationship with prognosis.

Detailed Description

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Conditions

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Cardiac Magnetic Resonance Myocardial Infarction with Nonobstructive Coronary Arteries Strain Extracellular Volume

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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diagnosed with MINOCA and completed with cardiac magnetic resonance

Cardiac MRI

Intervention Type OTHER

Patients with a diagnosis of MINOCA and completed CMR were included in this study

Interventions

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Cardiac MRI

Patients with a diagnosis of MINOCA and completed CMR were included in this study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Complete CMR during hospitalization;
2. CAG results suggesting coronary stenosis of less than 50%;
3. peak hsTnT above the 99th percentile.

Exclusion Criteria

* CMR image sequences are missing or of poor quality.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Affiliated Hospital of Xuzhou Medical University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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The Affiliated Hospital of Xuzhou Medical University

Xuzhou, Jiangsu, China

Site Status

Countries

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China

References

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Chen L, Ge L, Abdu FA, Du X, Liu J, Chen W, Lu Y, Che W. Prognostic value of CMR-derived extracellular volume in myocardial infarction with non-obstructive coronary arteries. Int J Cardiol. 2025 Oct 15;437:133528. doi: 10.1016/j.ijcard.2025.133528. Epub 2025 Jun 18.

Reference Type DERIVED
PMID: 40541789 (View on PubMed)

Chen L, Qiu B, Abdu FA, Liu L, Zhang W, Wang C, Alifu J, Qi P, Che W, Lu Y. Prognostic Value of Strain by Tissue Tracking Cardiac Magnetic Resonance in Myocardial Infarction With Nonobstructive Coronary Arteries. J Am Heart Assoc. 2025 Apr 15;14(8):e039395. doi: 10.1161/JAHA.124.039395. Epub 2025 Apr 7.

Reference Type DERIVED
PMID: 40194976 (View on PubMed)

Other Identifiers

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CMR in MINOCA

Identifier Type: -

Identifier Source: org_study_id

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